| Literature DB >> 18441001 |
Margarita C Theodoropoulou1, Pantelis G Bagos, Ioannis C Spyropoulos, Stavros J Hamodrakas.
Abstract
UNLABELLED: gpDB is a publicly accessible, relational database, containing information about G-proteins, G-protein coupled receptors (GPCRs) and effectors, as well as information concerning known interactions between these molecules. The sequences are classified according to a hierarchy of different classes, families and subfamilies based on literature search. The main innovation besides the classification of G-proteins, GPCRs and effectors is the relational model of the database, describing the known coupling specificity of GPCRs to their respective alpha subunits of G-proteins, and also the specific interaction between G-proteins and their effectors, a unique feature not available in any other database. AVAILABILITY: http://bioinformatics.biol.uoa.gr/gpDB CONTACT: shamodr@biol.uoa.gr SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.Mesh:
Substances:
Year: 2008 PMID: 18441001 DOI: 10.1093/bioinformatics/btn206
Source DB: PubMed Journal: Bioinformatics ISSN: 1367-4803 Impact factor: 6.937