| Literature DB >> 18436779 |
Abstract
In plants, DNA methylation, histone modifications, and RNA interference play critically important roles in regulating chromatin structure, thereby profoundly affecting transcription and other molecular events. Recent advances in microarray and high-throughput sequencing technologies have enabled genome-wide studies of these pathways in great detail. The vast amounts of "epigenomic" data generated so far have provided new insights into the mechanisms and functions of these pathways and have broadened our understanding of the structure and organization of plant chromatin as a whole.Mesh:
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Year: 2008 PMID: 18436779 DOI: 10.1126/science.1153996
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728