| Literature DB >> 18434396 |
G Palacios1, J Hui, P L Quan, A Kalkstein, K S Honkavuori, A V Bussetti, S Conlan, J Evans, Y P Chen, D vanEngelsdorp, H Efrat, J Pettis, D Cox-Foster, E C Holmes, T Briese, W I Lipkin.
Abstract
Israel acute paralysis virus (IAPV) is associated with colony collapse disorder of honey bees. Nonetheless, its role in the pathogenesis of the disorder and its geographic distribution are unclear. Here, we report phylogenetic analysis of IAPV obtained from bees in the United States, Canada, Australia, and Israel and the establishment of diagnostic real-time PCR assays for IAPV detection. Our data indicate the existence of at least three distinct IAPV lineages, two of them circulating in the United States. Analysis of representatives from each proposed lineage suggested the possibility of recombination events and revealed differences in coding sequences that may have implications for virulence.Entities:
Mesh：
Substances：
Year: 2008 PMID： 18434396 PMCID： PMC2447087 DOI： 10.1128/JVI.00251-08
Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103