Literature DB >> 18433936

Association study of the CFH Y402H polymorphism with Alzheimer's disease.

Isabelle Le Fur1, Geoffroy Laumet, Florence Richard, Nathalie Fievet, Claudine Berr, Olivier Rouaud, Cécile Delcourt, Philippe Amouyel, Jean-Charles Lambert.   

Abstract

Several reports indicated that Alzheimer's disease (AD) and age-related macular degeneration (AMD) may share similar genetic and pathological features. We postulated that the functional Y402H polymorphism within the CFH gene and unambiguously recognised as a major genetic determinant of AMD, may also be a risk factor of AD. We analysed the association of this polymorphism with the AD risk in both prospective and cross-sectional studies. We were not able to detect such an association whatever the studied population, suggesting that the CFH gene is not a genetic determinant of AD.

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Year:  2008        PMID： 18433936     DOI： 10.1016/j.neurobiolaging.2008.03.003

Source DB:  PubMed          Journal:  Neurobiol Aging        ISSN： 0197-4580            Impact factor:   4.673


  12 in total

Review 1.  The role of glial cells and the complement system in retinal diseases and Alzheimer's disease: common neural degeneration mechanisms.

Authors:  Hannah Harvey; Szonya Durant
Journal:  Exp Brain Res       Date:  2014-09-03       Impact factor: 1.972

2.  Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways.

Authors:  Mark W Logue; Matthew Schu; Badri N Vardarajan; John Farrell; Kathryn L Lunetta; Gyungah Jun; Clinton T Baldwin; Margaret M Deangelis; Lindsay A Farrer
Journal:  Neurobiol Aging       Date:  2013-12-19       Impact factor: 4.673

Review 3.  Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD).

Authors:  Yuhai Zhao; Surjyadipta Bhattacharjee; Brandon M Jones; James M Hill; Christian Clement; Kumar Sambamurti; Prerna Dua; Walter J Lukiw
Journal:  Mol Neurobiol       Date:  2014-09-10       Impact factor: 5.590

4.  CFH Variants Affect Structural and Functional Brain Changes and Genetic Risk of Alzheimer's Disease.

Authors:  Deng-Feng Zhang; Jin Li; Huan Wu; Yue Cui; Rui Bi; He-Jiang Zhou; Hui-Zhen Wang; Chen Zhang; Dong Wang; Qing-Peng Kong; Tao Li; Yiru Fang; Tianzi Jiang; Yong-Gang Yao
Journal:  Neuropsychopharmacology       Date:  2015-08-05       Impact factor: 7.853

5.  Brain-derived neurotrophic factor in patients with advanced age-related macular degeneration.

Authors:  Mehrdad Afarid; Mohammad Torabi-Nami; Alijan Nemati; Amir Khosravi; Mahyar Malekzadeh
Journal:  Int J Ophthalmol       Date:  2015-10-18       Impact factor: 1.779

6.  Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.

Authors:  Ian Catchpole; Volker Germaschewski; Jaimie Hoh Kam; Peter Lundh von Leithner; Susannah Ford; Gerald Gough; Peter Adamson; Philip Overend; Jan Hilpert; Francisco J López; Yin Shan Eric Ng; Pete Coffey; Glen Jeffery
Journal:  PLoS One       Date:  2013-06-14       Impact factor: 3.240

7.  Systemic and Ocular Long Pentraxin 3 in Patients with Age-Related Macular Degeneration.

Authors:  Helene Bæk Juel; Carsten Faber; Lea Munthe-Fog; Simone Bastrup-Birk; Alexander Lynge Reese-Petersen; Mads Krüger Falk; Amardeep Singh; Torben Lykke Sørensen; Peter Garred; Mogens Holst Nissen
Journal:  PLoS One       Date:  2015-07-15       Impact factor: 3.240

8.  Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment.

Authors:  Jon B Toledo; Ané Korff; Leslie M Shaw; John Q Trojanowski; Jing Zhang
Journal:  Alzheimers Res Ther       Date:  2014-06-23       Impact factor: 6.982

Review 9.  Understanding AMD by analogy: systematic review of lipid-related common pathogenic mechanisms in AMD, AD, AS and GN.

Authors:  Qinyuan Xu; Sijia Cao; Sanjeeva Rajapakse; Joanne A Matsubara
Journal:  Lipids Health Dis       Date:  2018-01-04       Impact factor: 3.876

10.  An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism.

Authors:  Bareng A S Nonyane; Dorothea Nitsch; John C Whittaker; Reecha Sofat; Liam Smeeth; Usha Chakravarthy; Astrid E Fletcher
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-12-30       Impact factor: 4.799
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