Literature DB >> 1841660

Informational drugs: a new concept in pharmacology.

J S Cohen1.   

Abstract

Drugs that contain information encoded in them are intended to interfere with great specificity in the transfer of information within the cell, thus providing selective therapeutic advantage. It is proposed that such drugs can be classified as informational drugs.

Mesh：

Substances：

Year:  1991        PMID： 1841660     DOI： 10.1089/ard.1991.1.191

Source DB:  PubMed          Journal:  Antisense Res Dev        ISSN： 1050-5261


  9 in total

1.  Modulation of human interferon-gamma biosynthesis by antisense oligodeoxynucleotides.

Authors:  C M Boeve; M De Ley
Journal:  Mol Biotechnol       Date:  2000-02       Impact factor: 2.695

2.  Inhibition of HPV-16 E6/E7 immortalization of normal keratinocytes by hairpin ribozymes.

Authors:  L M Alvarez-Salas; A E Cullinan; A Siwkowski; A Hampel; J A DiPaolo
Journal:  Proc Natl Acad Sci U S A       Date:  1998-02-03       Impact factor: 11.205

3.  PEGylation of therapeutic oligonucletides: From linear to highly branched PEG architectures.

Authors:  Xueguang Lu; Ke Zhang
Journal:  Nano Res       Date:  2018-07-06       Impact factor: 8.897

Review 4.  The chemical evolution of oligonucleotide therapies of clinical utility.

Authors:  Anastasia Khvorova; Jonathan K Watts
Journal:  Nat Biotechnol       Date:  2017-02-27       Impact factor: 54.908

5.  Precision Tuning of DNA- and Poly(ethylene glycol)-Based Nanoparticles via Coassembly for Effective Antisense Gene Regulation.

Authors:  Dali Wang; Xueguang Lu; Fei Jia; Xuyu Tan; Xiaoya Sun; Xueyan Cao; Francesco Wai; Chuan Zhang; Ke Zhang
Journal:  Chem Mater       Date:  2017-11-18       Impact factor: 9.811

6.  Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing.

Authors:  Frank Rigo; Yimin Hua; Seung J Chun; Thazha P Prakash; Adrian R Krainer; C Frank Bennett
Journal:  Nat Chem Biol       Date:  2012-04-15       Impact factor: 15.040

7.  Nucleic Acid Therapeutics for Neurological Diseases.

Authors:  Jonathan K Watts; Robert H Brown; Anastasia Khvorova
Journal:  Neurotherapeutics       Date:  2019-04       Impact factor: 7.620

8.  Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers.

Authors:  Chengxi Li; Alex J Callahan; Mark D Simon; Kyle A Totaro; Alexander J Mijalis; Kruttika-Suhas Phadke; Genwei Zhang; Nina Hartrampf; Carly K Schissel; Ming Zhou; Hong Zong; Gunnar J Hanson; Andrei Loas; Nicola L B Pohl; David E Verhoeven; Bradley L Pentelute
Journal:  Nat Commun       Date:  2021-07-20       Impact factor: 14.919

Review 9.  The role of the 5' untranslated region of eukaryotic messenger RNAs in translation and its investigation using antisense technologies.

Authors:  K Pantopoulos; H E Johansson; M W Hentze
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1994
  9 in total

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