Literature DB >> 1841601

Study of an additional 58 DNA markers in five human populations from four continents.

A M Bowcock1, J M Hebert, J L Mountain, J R Kidd, J Rogers, K K Kidd, L L Cavalli-Sforza.   

Abstract

One hundred DNA polymorphisms from 73 loci (42 genes and 31 anonymous DNA segments) were investigated in five populations (Biaka and Mbuti Pygmies, Melanesians, Chinese and Caucasoids). Data for 47 polymorphisms, including 42 of those discussed here, were described previously [Bowcock et al 1987]. Here we report statistical quantities of genetic importance for each gene and population. The average FST for the 100 markers is 0.137 and the average heterozygosity is 0.325. When known genes and anonymous segments are compared there is no significant difference in the average FST values or in the average heterozygosities.

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Year:  1991        PMID: 1841601

Source DB:  PubMed          Journal:  Gene Geogr        ISSN: 0394-249X


  13 in total

1.  Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations.

Authors:  K A Goddard; P J Hopkins; J M Hall; J S Witte
Journal:  Am J Hum Genet       Date:  2000-01       Impact factor: 11.025

2.  Multilocus genotypes, a tree of individuals, and human evolutionary history.

Authors:  J L Mountain; L L Cavalli-Sforza
Journal:  Am J Hum Genet       Date:  1997-09       Impact factor: 11.025

3.  An apportionment of human DNA diversity.

Authors:  G Barbujani; A Magagni; E Minch; L L Cavalli-Sforza
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-29       Impact factor: 11.205

4.  Ethnic-affiliation estimation by use of population-specific DNA markers.

Authors:  M D Shriver; M W Smith; L Jin; A Marcini; J M Akey; R Deka; R E Ferrell
Journal:  Am J Hum Genet       Date:  1997-04       Impact factor: 11.025

5.  Effects of worldwide population subdivision on ALDH2 linkage disequilibrium.

Authors:  R J Peterson; D Goldman; J C Long
Journal:  Genome Res       Date:  1999-09       Impact factor: 9.043

6.  Kinship bioassay on hypervariable loci in blacks and Caucasians.

Authors:  N E Morton; A Collins; I Balazs
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205

7.  Incorrect specification of marker allele frequencies: effects on linkage analysis.

Authors:  N B Freimer; L A Sandkuijl; S M Blower
Journal:  Am J Hum Genet       Date:  1993-06       Impact factor: 11.025

8.  Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus.

Authors:  Stephanie M Fullerton; Angelika Bartoszewicz; Gustavo Ybazeta; Yukio Horikawa; Graeme I Bell; Kenneth K Kidd; Nancy J Cox; Richard R Hudson; Anna Di Rienzo
Journal:  Am J Hum Genet       Date:  2002-03-12       Impact factor: 11.025

9.  Inference of human evolution through cladistic analysis of nuclear DNA restriction polymorphisms.

Authors:  J L Mountain; L L Cavalli-Sforza
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-05       Impact factor: 11.205

10.  Evolution of haplotypes at the DRD2 locus.

Authors:  C M Castiglione; A S Deinard; W C Speed; G Sirugo; H C Rosenbaum; Y Zhang; D K Grandy; E L Grigorenko; B Bonne-Tamir; A J Pakstis
Journal:  Am J Hum Genet       Date:  1995-12       Impact factor: 11.025

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