Literature DB >> 18415016

Concise synthesis of the pentasaccharide O-antigen of Escherichia coli O83:K24:H31 present in the Colinfant vaccine.

Pintu Kumar Mandal1, Anup Kumar Misra.   

Abstract

A block synthetic approach is presented for the synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O83:K24:H31 strain, present in the "Colifant" vaccine. The target pentasaccharide has been synthesized by coupling a disaccharide with a trisaccharide in excellent yield. Yields are quite satisfactory in all intermediate steps.

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Year:  2008        PMID: 18415016     DOI: 10.1007/s10719-008-9120-1

Source DB:  PubMed          Journal:  Glycoconj J        ISSN: 0282-0080            Impact factor:   2.916


  23 in total

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Review 4.  Diarrheagenic Escherichia coli.

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Authors:  B Jann; A S Shashkov; M Hahne; H Kochanowski; K Jann
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