Literature DB >> 18406813

Angiotensin II signal transduction: Stimulation of multiple mitogen-activated protein kinase pathways.

U Schmitz1, B C Berk.   

Abstract

Angiotensin II (AngII)( *) is the main effector of the renin-angiotensin system and influences cell growth, migration, differentiation, and apoptosis. The mitogen-activated protein (MAP) kinase family of serine-threonine kinases integrates diverse extracellular stimuli and is involved in the regulation of cell growth and apoptosis. AngII regulates activity of the MAP kinase family members extracellular regulated kinases (ERK1/2) and c-Jun N-terminal kinase (JNK). This review discusses the signal transduction pathways leading to ERK1/2 and JNK activation by AngII.

Entities:  

Year:  1997        PMID： 18406813     DOI： 10.1016/s1043-2760(97)00101-x

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  9 in total

1.  Rab1 GTPase regulates phenotypic modulation of pulmonary artery smooth muscle cells by mediating the transport of angiotensin II type 1 receptor under hypoxia.

Authors:  Hongjin Yin; Qi Li; Guisheng Qian; Yaoli Wang; Yuncheng Li; Guangyu Wu; Guansong Wang
Journal:  Int J Biochem Cell Biol       Date:  2010-11-21       Impact factor: 5.085

2.  Angiotensin II inhibits activity of human organic anion transporter 3 through activation of protein kinase Calpha: accelerating endocytosis of the transporter.

Authors:  Peng Duan; Shanshan Li; Guofeng You
Journal:  Eur J Pharmacol       Date:  2009-10-28       Impact factor: 4.432

Review 3.  Managing kidney disease with blood-pressure control.

Authors:  Elke Wühl; Franz Schaefer
Journal:  Nat Rev Nephrol       Date:  2011-06-21       Impact factor: 28.314

4.  Heparin inhibits angiotensin II-induced vasoconstriction on isolated mouse mesenteric resistance arteries through Rho-A- and PKA-dependent pathways.

Authors:  Hui Xie-Zukauskas; Jharna Das; Billie Lou Short; J Silvio Gutkind; Patricio E Ray
Journal:  Vascul Pharmacol       Date:  2012-12-23       Impact factor: 5.773

5.  Angiotensin-converting enzyme-induced activation of local angiotensin signaling is required for ascending aortic aneurysms in fibulin-4-deficient mice.

Authors:  Yoshito Yamashiro; Christina L Papke; Yuichi Ikeda; Jianbin Huang; Yanling Lin; Miteshkumar Patel; Tadashi Inagami; Victoria P Le; Jessica E Wagenseil; Hiromi Yanagisawa
Journal:  Sci Transl Med       Date:  2013-05-01       Impact factor: 17.956

6.  Exendin-4 Prevents Vascular Smooth Muscle Cell Proliferation and Migration by Angiotensin II via the Inhibition of ERK1/2 and JNK Signaling Pathways.

Authors:  Kosuke Nagayama; Yoji Kyotani; Jing Zhao; Satoyasu Ito; Kentaro Ozawa; Francesco A Bolstad; Masanori Yoshizumi
Journal:  PLoS One       Date:  2015-09-17       Impact factor: 3.240

7.  Targeting the mitogen-activated protein kinase-mediated vascular smooth muscle cell remodeling by angiotensin II.

Authors:  Masanori Yoshizumi; Yoji Kyotani; Jing Zhao; Kiichi Nakahira
Journal:  Ann Transl Med       Date:  2020-03

8.  Allele-specific differences in activity of a novel cannabinoid receptor 1 (CNR1) gene intronic enhancer in hypothalamus, dorsal root ganglia, and hippocampus.

Authors:  Gemma Nicoll; Scott Davidson; Lynne Shanley; Ben Hing; Marissa Lear; Peter McGuffin; Ruth Ross; Alasdair MacKenzie
Journal:  J Biol Chem       Date:  2012-02-23       Impact factor: 5.157

Review 9.  The role of local renin-angiotensin system in arterial chemoreceptors in sleep-breathing disorders.

Authors:  Man Lung Fung
Journal:  Front Physiol       Date:  2014-09-05       Impact factor: 4.566
  9 in total

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