Literature DB >> 18404330

Antitubercular triterpenes and phytosterols from Pandanus tectorius Soland. var. laevis.

Mario A Tan1, Hiromitsu Takayama, Norio Aimi, Mariko Kitajima, Scott G Franzblau, Maribel G Nonato.   

Abstract

Bioassay-guided chromatographic purification of the antitubercular chloroform extract of Pandanus tectorius Soland. var. laevis leaves afforded a new tirucallane-type triterpene, 24,24-dimethyl-5 beta-tirucall-9(11),25-dien-3-one (1), squalene and a mixture of the phytosterols stigmasterol and beta-sitosterol. Microplate Alamar Blue Assay (MABA) showed that 1 inhibited the growth of Mycobacterium tuberculosis H(37)Rv with a MIC of 64 microg/mL, while squalene and the sterol mixture have MICs of 100 and 128 microg/mL, respectively.

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Year:  2007        PMID： 18404330     DOI： 10.1007/s11418-007-0218-8

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  3 in total

1.  Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae).

Authors:  Jonel P Saludes; Mary J Garson; Scott G Franzblau; Alicia M Aguinaldo
Journal:  Phytother Res       Date:  2002-11       Impact factor: 5.878

2.  Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium.

Authors:  L Collins; S G Franzblau
Journal:  Antimicrob Agents Chemother       Date:  1997-05       Impact factor: 5.191

3.  Isolation and characterization of two new alkaloids, norpandamarilactonine-A and -B, from Pandanus amaryllifolius by spectroscopic and synthetic methods.

Authors:  H Takayama; T Ichikawa; M Kitajima; M G Nonato; N Aimi
Journal:  J Nat Prod       Date:  2001-09       Impact factor: 4.050
  3 in total
  5 in total

1.  Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.

Authors:  Bharat B Aggarwal; Sahdeo Prasad; Simone Reuter; Ramaswamy Kannappan; Vivek R Yadev; Byoungduck Park; Ji Hye Kim; Subash C Gupta; Kanokkarn Phromnoi; Chitra Sundaram; Seema Prasad; Madan M Chaturvedi; Bokyung Sung
Journal:  Curr Drug Targets       Date:  2011-10       Impact factor: 3.465

2.  Tetrahdroxysqualene from Rhus taitensis shows antimycobacterial activity against Mycobacterium tuberculosis.

Authors:  Jeffrey C Noro; Louis R Barrows; Osia G Gideon; Chris M Ireland; Michael Koch; Teatulohi Matainaho; Pius Piskaut; Christopher D Pond; Tim S Bugni
Journal:  J Nat Prod       Date:  2008-08-19       Impact factor: 4.050

3.  The Modulatory Properties of Li-Ru-Kang Treatment on Hyperplasia of Mammary Glands Using an Integrated Approach.

Authors:  Shizhang Wei; Liqi Qian; Ming Niu; Honghong Liu; Yuxue Yang; Yingying Wang; Lu Zhang; Xuelin Zhou; Haotian Li; Ruilin Wang; Kun Li; Yanling Zhao
Journal:  Front Pharmacol       Date:  2018-06-19       Impact factor: 5.810

4.  Brassicasterol with Dual Anti-Infective Properties against HSV-1 and Mycobacterium tuberculosis, and Cardiovascular Protective Effect: Nonclinical In Vitro and In Silico Assessments.

Authors:  Sherif T S Hassan
Journal:  Biomedicines       Date:  2020-05-24

5.  Neuroprotective effects on amyloid-beta induced cytotoxicity of Pandanus clementis Merr.

Authors:  Mario A Tan; Byron Leander U Tan; Maribel G Nonato; Seong Soo A An
Journal:  3 Biotech       Date:  2021-06-13       Impact factor: 2.893
  5 in total

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