Literature DB >> 12410555

Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae).

Jonel P Saludes1, Mary J Garson, Scott G Franzblau, Alicia M Aguinaldo.   

Abstract

A crude ethanol extract and hexane fraction from Morinda citrifolia Linn. (Rubiaceae) show antitubercular activity. The major constituents of the hexane fraction are E-phytol, cycloartenol, stigmasterol, beta-sitosterol, campesta-5,7,22-trien-3beta-ol and the ketosteroids stigmasta-4-en-3-one and stigmasta-4-22-dien-3-one. E-Phytol, a mixture of the two ketosteroids, and the epidioxysterol derived from campesta-5,7,22-trien-3beta-ol all show pronounced antitubercular activity. Copyright 2002 John Wiley & Sons, Ltd.

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Year:  2002        PMID： 12410555     DOI： 10.1002/ptr.1003

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


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