Literature DB >> 18395861

Human regulatory T cells and autoimmunity.

Cristina M Costantino1, Clare M Baecher-Allan, David A Hafler.   

Abstract

CD4+CD25+ regulatory T cells (Treg) appear to be critical in regulating immune responses to self-antigens. Treg deficiency is associated with several human autoimmune diseases. Although substantial progress has been made in the study of murine and human Treg, their fundamental mechanism of action remains unknown. In this review, we discuss the phenotype of human natural Treg, their functional mechanism, and their role in autoimmune disease.

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Year:  2008        PMID： 18395861      PMCID： PMC2752283          DOI： 10.1002/eji.200738104

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  29 in total

1.  Inhibition of human CD4(+)CD25(+high) regulatory T cell function.

Authors:  Clare Baecher-Allan; Vissia Viglietta; David A Hafler
Journal:  J Immunol       Date:  2002-12-01       Impact factor: 5.422

2.  Analysis of CD4+CD25+ cell population in the thymus from myasthenia gravis patients.

Authors:  A Balandina; A Saoudi; P Dartevelle; S Berrih-Aknin
Journal:  Ann N Y Acad Sci       Date:  2003-09       Impact factor: 5.691

Review 3.  On 'reactivity' versus 'tolerance'.

Authors:  Rolf M Zinkernagel
Journal:  Immunol Cell Biol       Date:  2004-08       Impact factor: 5.126

4.  CD4+CD25high regulatory cells in human peripheral blood.

Authors:  C Baecher-Allan; J A Brown; G J Freeman; D A Hafler
Journal:  J Immunol       Date:  2001-08-01       Impact factor: 5.422

5.  Activated human T cells accomplish MHC class II expression through T cell-specific occupation of class II transactivator promoter III.

Authors:  Tjadine M Holling; Nienke van der Stoep; Edwin Quinten; Peter J van den Elsen
Journal:  J Immunol       Date:  2002-01-15       Impact factor: 5.422

6.  Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis.

Authors:  Duojia Cao; Vivianne Malmström; Clare Baecher-Allan; David Hafler; Lars Klareskog; Christina Trollmo
Journal:  Eur J Immunol       Date:  2003-01       Impact factor: 5.532

Review 7.  Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis.

Authors:  Eleonora Gambineri; Troy R Torgerson; Hans D Ochs
Journal:  Curr Opin Rheumatol       Date:  2003-07       Impact factor: 5.006

8.  Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin.

Authors:  J R Lamb; B J Skidmore; N Green; J M Chiller; M Feldmann
Journal:  J Exp Med       Date:  1983-05-01       Impact factor: 14.307

9.  Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells.

Authors:  Helmut Jonuleit; Edgar Schmitt; Hacer Kakirman; Michael Stassen; Jürgen Knop; Alexander H Enk
Journal:  J Exp Med       Date:  2002-07-15       Impact factor: 14.307

10.  Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].

Authors:  Detlef Dieckmann; Cord Henrik Bruett; Heidi Ploettner; Manfred Bernhard Lutz; Gerold Schuler
Journal:  J Exp Med       Date:  2002-07-15       Impact factor: 14.307
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  57 in total

Review 1.  Inflammation and adaptive immunity in Parkinson's disease.

Authors:  R Lee Mosley; Jessica A Hutter-Saunders; David K Stone; Howard E Gendelman
Journal:  Cold Spring Harb Perspect Med       Date:  2012-01       Impact factor: 6.915

2.  Antigenic challenge in the etiology of autoimmune disease in women.

Authors:  Mary A M Rogers; Deborah A Levine; Neil Blumberg; Gwenith G Fisher; Mohammed Kabeto; Kenneth M Langa
Journal:  J Autoimmun       Date:  2011-08-30       Impact factor: 7.094

3.  Characterization of MT-2 cells as a human regulatory T cell-like cell line.

Authors:  Ryoko Hamano; Xueqiang Wu; Yitao Wang; Joost J Oppenheim; Xin Chen
Journal:  Cell Mol Immunol       Date:  2014-12-29       Impact factor: 11.530

4.  Fennel main constituent, trans‑anethole treatment against LPS‑induced acute lung injury by regulation of Th17/Treg function.

Authors:  Sichao Zhang; Xi Chen; Ichinkhorloo Devshilt; Qi Yun; Cong Huang; Lijun An; Sosorburam Dorjbat; Xin He
Journal:  Mol Med Rep       Date:  2018-06-07       Impact factor: 2.952

Review 5.  Regulation generation: the suppressive functions of human regulatory T cells.

Authors:  Wendy A Goodman; Kevin D Cooper; Thomas S McCormick
Journal:  Crit Rev Immunol       Date:  2012       Impact factor: 2.214

6.  Collagen-induced arthritis: severity and immune response attenuation using multivalent N-acetyl glucosamine.

Authors:  J Richter; K Capková; V Hříbalová; L Vannucci; I Danyi; M Malý; A Fišerová
Journal:  Clin Exp Immunol       Date:  2014-07       Impact factor: 4.330

7.  Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.

Authors:  Jens Y Humrich; Henner Morbach; Reinmar Undeutsch; Philipp Enghard; Stefan Rosenberger; Olivia Weigert; Lutz Kloke; Juliane Heimann; Timo Gaber; Susan Brandenburg; Alexander Scheffold; Jochen Huehn; Andreas Radbruch; Gerd-Rüdiger Burmester; Gabriela Riemekasten
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-14       Impact factor: 11.205

Review 8.  Induction of immune tolerance by activation of CD8+ T suppressor/regulatory cells in lupus-prone mice.

Authors:  Brian J Skaggs; Ram Pyare Singh; Bevra H Hahn
Journal:  Hum Immunol       Date:  2008-09-24       Impact factor: 2.850

Review 9.  Insights into the heterogeneity of human B cells: diverse functions, roles in autoimmunity, and use as therapeutic targets.

Authors:  Jennifer H Anolik; R John Looney; Frances E Lund; Troy D Randall; Iñaki Sanz
Journal:  Immunol Res       Date:  2009-04-07       Impact factor: 2.829

10.  Age-related changes in arthritis susceptibility and severity in a murine model of rheumatoid arthritis.

Authors:  Oktavia Tarjanyi; Ferenc Boldizsar; Peter Nemeth; Katalin Mikecz; Tibor T Glant
Journal:  Immun Ageing       Date:  2009-06-11       Impact factor: 6.400
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