BACKGROUND: Patent ductus arteriosus (PDA) is associated with morbidity and mortality in premature neonates. METHODS: The effect of serial echocardiography performed by a neonatologist and early targeted medical PDA treatment was evaluated and compared to historical controls. One hundred ninety-two infants <1,500 g were included and 45 infants had a PDA. RESULTS: Serial echocardiography allowed significantly earlier identification and treatment of PDA versus awaiting the evolution of clinical signs. Severe intraventricular haemorrhage and ventilator days were significantly decreased in the studied cohort following the introduction of echocardiography. In addition, hospital stay was also reduced in the non-PDA group and other outcomes were unchanged. CONCLUSION: Serial echocardiography for PDA evaluation, performed by a neonatologist trained in echo, may reduce morbidity in preterm infant.
BACKGROUND: Patent ductus arteriosus (PDA) is associated with morbidity and mortality in premature neonates. METHODS: The effect of serial echocardiography performed by a neonatologist and early targeted medical PDA treatment was evaluated and compared to historical controls. One hundred ninety-two infants <1,500 g were included and 45 infants had a PDA. RESULTS: Serial echocardiography allowed significantly earlier identification and treatment of PDA versus awaiting the evolution of clinical signs. Severe intraventricular haemorrhage and ventilator days were significantly decreased in the studied cohort following the introduction of echocardiography. In addition, hospital stay was also reduced in the non-PDA group and other outcomes were unchanged. CONCLUSION: Serial echocardiography for PDA evaluation, performed by a neonatologist trained in echo, may reduce morbidity in preterm infant.
Authors: Marina Maccagnano Zamith; Simone de Araujo Negreiros Figueira; Allan Chiaratti de Oliveira; Cristiane Metolina; Junia Sampel de Castro; Cristina Nunes Dos Santos; Ana Leticia de Oliveira Abrahão de Capo; Valdir Ambrósio Moisés Journal: J Pediatr (Rio J) Date: 2019-06-06 Impact factor: 2.990
Authors: Willem P de Boode; Yogen Singh; Samir Gupta; Topun Austin; Kajsa Bohlin; Eugene Dempsey; Alan Groves; Beate Horsberg Eriksen; David van Laere; Zoltan Molnar; Eirik Nestaas; Sheryle Rogerson; Ulf Schubert; Cécile Tissot; Robin van der Lee; Bart van Overmeire; Afif El-Khuffash Journal: Pediatr Res Date: 2016-06-08 Impact factor: 3.756
Authors: David van Laere; Bart van Overmeire; Samir Gupta; Afif El-Khuffash; Marilena Savoia; Patrick J McNamara; Christoph E Schwarz; Willem P de Boode Journal: Pediatr Res Date: 2018-07 Impact factor: 3.756