Literature DB >> 18384915

The antihypertensive effect of peptides: a novel alternative to drugs?

Fang Hong1, Luo Ming, Sheng Yi, Li Zhanxia, Wu Yongquan, Liu Chi.   

Abstract

Many types of bioactive peptides that inhibit angiotensin I, angiotensin I converting enzyme (ACE) and Ang II type 1 receptor (AT1) in the cardiovascular system contribute to the prevention and treatment of hypertension. These inhibitory peptides are derived from many food proteins or artificial synthetic products. Further research examining the bioavailability of ACE inhibitory peptides will lead to the development of more effective ACE inhibitory peptides and foods. Our research also demonstrates that ACE inhibitory peptide LAP may lower blood pressure with no adverse effects.

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Year:  2008        PMID: 18384915     DOI: 10.1016/j.peptides.2008.02.005

Source DB:  PubMed          Journal:  Peptides        ISSN: 0196-9781            Impact factor:   3.750


  36 in total

Review 1.  Performance of Black Bengal goat: a 50-year review.

Authors:  Md Emran Hossain
Journal:  Trop Anim Health Prod       Date:  2021-01-05       Impact factor: 1.559

2.  Red meat, poultry, and egg consumption with the risk of hypertension: a meta-analysis of prospective cohort studies.

Authors:  Yi Zhang; Dian-Zhong Zhang
Journal:  J Hum Hypertens       Date:  2018-05-04       Impact factor: 3.012

3.  Use of small angle neutron scattering to study the interaction of angiotensin II with model membranes.

Authors:  Julia Preu; Timo Jaeger; Vasil M Garamus; Thomas Gutberlet
Journal:  Eur Biophys J       Date:  2011-02-03       Impact factor: 1.733

4.  Long-term intervention with Lactobacillus helveticus fermented milk reduces augmentation index in hypertensive subjects.

Authors:  T Jauhiainen; M Rönnback; H Vapaatalo; K Wuolle; H Kautiainen; P-H Groop; R Korpela
Journal:  Eur J Clin Nutr       Date:  2010-02-10       Impact factor: 4.016

5.  The effects of angiotensin-converting enzyme-inhibitory peptide LAP on the left common carotid artery remodeling in spontaneously hypertensive rats.

Authors:  F Hong; H Junling; S Yi; L Chi; Z Huan; D Yu Qing; L Lingxia; G Yang; L Ming
Journal:  Ir J Med Sci       Date:  2013-05-10       Impact factor: 1.568

6.  Pilot-scale production of soybean oligopeptides and antioxidant and antihypertensive effects in vitro and in vivo.

Authors:  Mu-Yi Cai; Rui-Zeng Gu; Chen-Yue Li; Yong Ma; Zhe Dong; Wen-Ying Liu; Zhen-Tao Jin; Jun Lu; Wei-Xue Yi
Journal:  J Food Sci Technol       Date:  2012-04-25       Impact factor: 2.701

7.  Identification of tripeptides recognized by the PDZ domain of Dishevelled.

Authors:  Ho-Jin Lee; Nick X Wang; Youming Shao; Jie J Zheng
Journal:  Bioorg Med Chem       Date:  2009-01-03       Impact factor: 3.641

8.  Seed-specific expression of truncated OsGAD2 produces GABA-enriched rice grains that influence a decrease in blood pressure in spontaneously hypertensive rats.

Authors:  Kazuhito Akama; Junko Kanetou; Shunsuke Shimosaki; Kouhei Kawakami; Satoru Tsuchikura; Fumio Takaiwa
Journal:  Transgenic Res       Date:  2009-05-12       Impact factor: 2.788

9.  Production of defatted palm kernel cake protein hydrolysate as a valuable source of natural antioxidants.

Authors:  Mohammad Zarei; Afshin Ebrahimpour; Azizah Abdul-Hamid; Farooq Anwar; Nazamid Saari
Journal:  Int J Mol Sci       Date:  2012-06-29       Impact factor: 6.208

10.  The effect of carbohydrate and marine peptide hydrolysate co-ingestion on endurance exercise metabolism and performance.

Authors:  Jason C Siegler; Richard Page; Mark Turner; Nigel Mitchell; Adrian W Midgely
Journal:  J Int Soc Sports Nutr       Date:  2013-05-31       Impact factor: 5.150

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