Literature DB >> 18382385

HIV-1 drug resistance in HIV-1-infected children in the United Kingdom from 1998 to 2004.

Rana Chakraborty1, Colette J Smith, David Dunn, Hannah Green, Trinh Duong, Katja Doerholt, Andrew Riordon, Hermione Lyall, Pat Tookey, Karina Butler, Caroline A Sabin, Di Gibb, Deenan Pillay.   

Abstract

We reviewed HIV-1 genotypes from 200 of 979 (20%) HIV-infected children in the U.K. Collaborative HIV in Pediatric Study (CHIPS) cohort (343 resistance tests). Three of 44 samples had major primary resistance mutations before antiretroviral therapy. Three-class resistance was noted in 42 samples (14.1%). Our study also highlighted underutilization of testing and the need for prompt genotyping after drug discontinuation which may have lead to an underestimation of HIV-1 resistance.

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Year:  2008        PMID： 18382385     DOI： 10.1097/INF.0b013e3181646d6f

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  11 in total

1.  Prevalence of drug resistance in human immunodeficiency virus type 1-infected treatment-naive children in Pune, India.

Authors:  Mukesh Kumar; Sourav Sen; Rakesh K Gupta; Devidas Chaturbhuj; Srikanth P Tripathy; Ramesh S Paranjape
Journal:  AIDS Res Hum Retroviruses       Date:  2014-02-07       Impact factor: 2.205

2.  Outcomes after viral load rebound on first-line antiretroviraltreatment in children with HIV in the UK and Ireland: an observational cohort study.

Authors:  Tristan Childs; Delane Shingadia; Ruth Goodall; Katja Doerholt; Hermione Lyall; Trinh Duong; Ali Judd; Di M Gibb; Intira Jeannie Collins
Journal:  Lancet HIV       Date:  2015-04       Impact factor: 12.767

3.  Sexual risk behavior among youth with perinatal HIV infection in the United States: predictors and implications for intervention development.

Authors:  Katherine Tassiopoulos; Anna-Barbara Moscicki; Claude Mellins; Deborah Kacanek; Kathleen Malee; Susannah Allison; Rohan Hazra; George K Siberry; Renee Smith; Mary Paul; Russell B Van Dyke; George R Seage
Journal:  Clin Infect Dis       Date:  2012-11-07       Impact factor: 9.079

4.  First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial.

Authors:  Abdel Babiker; Hannah Castro nee Green; Alexandra Compagnucci; Susan Fiscus; Carlo Giaquinto; Diana M Gibb; Lynda Harper; Linda Harrison; Michael Hughes; Ross McKinney; Ann Melvin; Lynne Mofenson; Yacine Saidi; M Elizabeth Smith; Gareth Tudor-Williams; A Sarah Walker
Journal:  Lancet Infect Dis       Date:  2011-01-31       Impact factor: 25.071

5.  Clinical Status of Adolescents with Perinatal HIV at Transfer to Adult Care in the UK/Ireland.

Authors:  Intira Jeannie Collins; Caroline Foster; Anna Tostevin; Pat Tookey; Andrew Riordan; David Dunn; D M Gibb; Ali Judd
Journal:  Clin Infect Dis       Date:  2017-04-15       Impact factor: 9.079

6.  Experiencing antiretroviral adherence: helping healthcare staff better understand adherence to paediatric antiretrovirals.

Authors:  Benjamin R Phelps; Sarah J Hathcock; Jennifer Werdenberg; Gordon E Schutze
Journal:  J Int AIDS Soc       Date:  2010-12-06       Impact factor: 5.396

7.  HIV Drug Resistance-Associated Mutations in Antiretroviral Naïve HIV-1-Infected Latin American Children.

Authors:  Luis E Soto-Ramirez; Roberto Rodriguez-Diaz; D Robert Harris; Rohan Hazra
Journal:  Adv Virol       Date:  2011-01-18

8.  Decline in CD4 T lymphocytes with monotherapy bridging strategy for non-adherent adolescents living with HIV infection: Results of the IMPAACT P1094 randomized trial.

Authors:  Allison L Agwu; Meredith G Warshaw; Elizabeth J McFarland; George K Siberry; Ann J Melvin; Andrew A Wiznia; Lee Fairlie; Sandra Boyd; Paul Harding; Hans M L Spiegel; Elaine J Abrams; Vincent J Carey
Journal:  PLoS One       Date:  2017-06-12       Impact factor: 3.240

9.  Impact of Clinical Parameters in the Intrahost Evolution of HIV-1 Subtype B in Pediatric Patients: A Machine Learning Approach.

Authors:  Patricia Rojas Sánchez; Alberto Cobos; Marisa Navaro; José Tomas Ramos; Israel Pagán; África Holguín
Journal:  Genome Biol Evol       Date:  2017-10-01       Impact factor: 3.416

10.  Relationship between viral load and behavioral measures of adherence to antiretroviral therapy in children living with human immunodeficiency virus in Latin America.

Authors:  Horacio A Duarte; Donald Robert Harris; Katherine Tassiopoulos; Erin Leister; Silvia Fabiana Biason de Moura Negrini; Flávia Faleiro Ferreira; Maria Letícia Santos Cruz; Jorge Pinto; Susannah Allison; Rohan Hazra
Journal:  Braz J Infect Dis       Date:  2015-03-03       Impact factor: 3.257
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