Literature DB >> 18379226

Veterans Affairs intensive care unit risk adjustment model: validation, updating, recalibration.

Marta L Render1, James Deddens, Ron Freyberg, Peter Almenoff, Alfred F Connors, Douglas Wagner, Timothy P Hofer.   

Abstract

BACKGROUND: A valid metric is critical to measure and report intensive care unit (ICU) outcomes and drive innovation in a national system.
OBJECTIVES: To update and validate the Veterans Affairs (VA) ICU severity measure (VA ICU). RESEARCH
DESIGN: A validated logistic regression model was applied to two VA hospital data sets: 36,240 consecutive ICU admissions to a stratified random sample of moderate and large hospitals in 1999-2000 (cohort 1) and 81,964 cases from 42 VA Medical Centers in fiscal years 2002-2004 (cohort 2). The model was updated by adding diagnostic groups and expanding the source of admission variables. MEASURES: C statistic, Hosmer-Lemeshow goodness-of-fit statistic, and Brier's score measured predictive validity. Coefficients from the 1997 model were applied to predictors (fixed) in a logistic regression model. A 10 x 10 table compared cases with both VA ICU and National Surgical Quality Improvement Performance metrics. The standardized mortality ratios divided observed deaths by the sum of predicted mortality.
RESULTS: The fixed model in both cohorts had predictive validity (cohort 1: C statistic = 0.874, Hosmer-Lemeshow goodness-of-fit C statistic chi-square = 72.5; cohort 2: 0.876, 307), as did the updated model (cohort 2: C statistic = 0.887, Hosmer-Lemeshow goodness-of-fit C statistic chi-square = 39). In 7,411 cases with predictions in both systems, the standardized mortality ratio was similar (1.04 for VA ICU, 1.15 for National Surgical Quality Improvement Performance), and 92% of cases matched (+/-1 decile) when ordered by deciles of mortality. The VA ICU standardized mortality ratio correlates with the National Surgical Quality Improvement Performance standardized mortality ratio (r2 = .74). Variation in discharge and laboratory practices may affect performance measurement.
CONCLUSION: The VA ICU severity model has face, construct, and predictive validity.

Mesh:

Year:  2008        PMID: 18379226     DOI: 10.1097/CCM.0b013e318169f290

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  30 in total

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Authors:  Mohammed Saeed; Mauricio Villarroel; Andrew T Reisner; Gari Clifford; Li-Wei Lehman; George Moody; Thomas Heldt; Tin H Kyaw; Benjamin Moody; Roger G Mark
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3.  Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care.

Authors:  Theodore J Iwashyna; James F Burke; Jeremy B Sussman; Hallie C Prescott; Rodney A Hayward; Derek C Angus
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4.  Perioperative and ICU Healthcare Analytics within a Veterans Integrated System Network: a Qualitative Gap Analysis.

Authors:  Seshadri Mudumbai; Ferenc Ayer; Jerry Stefanko
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5.  The Effect of Intensive Care Unit Admission Patterns on Mortality-based Critical Care Performance Measures.

Authors:  Ian J Barbash; Tri Q Le; Francis Pike; Amber E Barnato; Derek C Angus; Jeremy M Kahn
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6.  The impact of paradoxical comorbidities on risk-adjusted mortality of Medicare beneficiaries with cardiovascular disease.

Authors:  Mary S Vaughan-Sarrazin; Xin Lu; Peter Cram
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7.  Variation in Postsepsis Readmission Patterns: A Cohort Study of Veterans Affairs Beneficiaries.

Authors:  Hallie C Prescott
Journal:  Ann Am Thorac Soc       Date:  2017-02

8.  Late Vasopressor Administration in Patients in the ICU: A Retrospective Cohort Study.

Authors:  Elizabeth M Viglianti; Sean M Bagshaw; Rinaldo Bellomo; Joanne McPeake; Daniel J Molling; Xiao Qing Wang; Sarah Seelye; Theodore J Iwashyna
Journal:  Chest       Date:  2020-04-09       Impact factor: 9.410

9.  Hospital-level variation in the development of persistent critical illness.

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Review 10.  Using existing data to address important clinical questions in critical care.

Authors:  Colin R Cooke; Theodore J Iwashyna
Journal:  Crit Care Med       Date:  2013-03       Impact factor: 7.598

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