| Literature DB >> 18378321 |
Michael Poyurovsky1, Sarit Faragian, Artashez Pashinian, Lilah Heidrach, Camil Fuchs, Ronit Weizman, Lorrin Koran.
Abstract
In this study we compared 15 patients with DSM-IV obsessive-compulsive disorder (OCD) and schizotypal personality disorder (SPD) and 31 non-SPD OCD patients. OCD-SPD patients had poorer insight, more negative symptoms, lower functioning, more antipsychotic augmentation and more first-degree relatives with schizophrenia-spectrum disorders. A distinct clinical phenotype of OCD associated with SPD should be considered when investigating etiopathogenetic mechanisms.Entities:
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Year: 2008 PMID： 18378321 DOI： 10.1016/j.psychres.2007.02.019
Source DB: PubMed Journal: Psychiatry Res ISSN： 0165-1781 Impact factor: 3.222