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Literature DB >> 18377900

Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst formation.

Christopher W Lipari¹, Jairo E Garcia, Yulian Zhao, Kimberly Thrift, Dhananjay Vaidya, Annabelle Rodriguez.

Abstract

Eleven patients underwent controlled ovarian hyperstimulation yielding 72 embryos for evaluation. Mean nitric oxide metabolite levels in the insemination media were 2.6 times higher in embryos that progressed to blastocysts by culture day 5 than in those that did not. A comparison of the receiver operating characteristic curves between morphological predictors and nitric oxide metabolite levels revealed a trend toward a stronger association of insemination media nitric oxide metabolite with blastocyst formation.

Entities: Chemical Disease Species

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Year: 2008 PMID： 18377900 PMCID： PMC3359095 DOI： 10.1016/j.fertnstert.2008.01.108

Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329

20 in total

Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst formation.

Review 1. In vitro development and metabolism of the human embryo up to the blastocyst stage.

Review 2. Nitric oxide in oocyte maturation, ovulation, fertilization, cleavage and implantation: a little dab'll do ya.

3. Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover.

4. Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential.

5. The Graduated Embryo Score (GES) predicts blastocyst formation and pregnancy rate from cleavage-stage embryos.

6. Non-invasive amino acid turnover predicts human embryo developmental capacity.

7. Nitric oxide as a regulator in preimplantation embryo development and apoptosis.

8. In vitro fertilization with single blastocyst-stage versus single cleavage-stage embryos.

9. Accuracy of day 3 criteria for selecting the best embryos.

10. Embryonic production of nitric oxide and its role in implantation: a pilot study.

Review 1. Non-invasive methods for embryo selection.

Review 2. Novel Insights on the Role of Nitric Oxide in the Ovary: A Review of the Literature.

Review 3. Select nutrients and their effects on conceptus development in mammals.