Literature DB >> 18376697

Blast injury in a civilian trauma setting is associated with a delay in diagnosis of traumatic brain injury.

Grant V Bochicchio1, Kimberly Lumpkins, James O'Connor, Marc Simard, Stacey Schaub, Anne Conway, Kelly Bochicchio, Thomas M Scalea.   

Abstract

High-pressure waves (blast) account for the majority of combat injuries and are becoming increasingly common in terrorist attacks. To our knowledge, there are no data evaluating the epidemiology of blast injury in a domestic nonterrorist setting. Data were analyzed retrospectively on patients admitted with any type of blast injury over a 10-year period at a busy urban trauma center. Injuries were classified by etiology of explosion and anatomical location. Eighty-nine cases of blast injury were identified in 57,392 patients (0.2%) treated over the study period. The majority of patients were male (78%) with a mean age of 40 +/- 17 years. The mean Injury Severity Score was 13 +/- 11 with an admission Trauma and Injury Severity Score of 0.9 +/- 0.2 and Revised Trauma Score of 7.5 +/- 0.8. The mean intensive care unit and hospital length of stay was 2 +/- 7 days and 4.6 +/- 10 days, respectively, with an overall mortality rate of 4.5 per cent. Private dwelling explosion [n = 31 (35%)] was the most common etiology followed by industrial pressure blast [n = 20 (22%)], industrial gas explosion [n = 16 (18%)], military training-related explosion [n = 15 (17%)], home explosive device [n = 8 (9%)], and fireworks explosion [n = 1 (1%)]. Maxillofacial injuries were the most common injury (n = 78) followed by upper extremity orthopedic (n = 29), head injury (n = 32), abdominal (n = 30), lower extremity orthopedic (n = 29), and thoracic (n = 19). The majority of patients with head injury [28 of 32 (88%)] presented with a Glasgow Coma Scale score of 15. CT scans on admission were initially positive for brain injury in 14 of 28 patients (50%). Seven patients (25%) who did not have a CT scan on admission had a CT performed later in their hospital course as a result of mental status change and were positive for traumatic brain injury (TBI). Three patients (11%) had a negative admission CT with a subsequently positive CT for TBI over the next 48 hours. The remaining four patients (14%) were diagnosed with skull fractures. All patients (n = 4) with an admission Glasgow Coma Scale score of less than 8 died from diffuse axonal injury. Blast injury is a complicated disease process, which may evolve over time, particularly with TBI. The missed injury rate for TBI in patients with a Glasgow Coma Scale score of 15 was 36 per cent. More studies are needed in the area of blast injury to better understand this disease process.

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Mesh:

Year:  2008        PMID: 18376697

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  13 in total

Review 1.  Neurological effects of blast injury.

Authors:  Ramona R Hicks; Stephanie J Fertig; Rebecca E Desrocher; Walter J Koroshetz; Joseph J Pancrazio
Journal:  J Trauma       Date:  2010-05

Review 2.  Primary blast injuries--an updated concise review.

Authors:  Daniel Dante Yeh; William P Schecter
Journal:  World J Surg       Date:  2012-05       Impact factor: 3.352

Review 3.  Update on TBI and Cognitive Impairment in Military Veterans.

Authors:  Gregory A Elder
Journal:  Curr Neurol Neurosci Rep       Date:  2015-10       Impact factor: 5.081

4.  An animal-to-human scaling law for blast-induced traumatic brain injury risk assessment.

Authors:  Aurélie Jean; Michelle K Nyein; James Q Zheng; David F Moore; John D Joannopoulos; Raúl Radovitzky
Journal:  Proc Natl Acad Sci U S A       Date:  2014-09-29       Impact factor: 11.205

5.  Civilian blast-related burn injuries.

Authors:  J N Patel; A Tan; P Dziewulski
Journal:  Ann Burns Fire Disasters       Date:  2016-03-31

6.  White matter compromise in veterans exposed to primary blast forces.

Authors:  Katherine H Taber; Robin A Hurley; Courtney C Haswell; Jared A Rowland; Susan D Hurt; Cory D Lamar; Rajendra A Morey
Journal:  J Head Trauma Rehabil       Date:  2015 Jan-Feb       Impact factor: 2.710

7.  Serum-based protein biomarkers in blast-induced traumatic brain injury spectrum disorder.

Authors:  Denes V Agoston; Mohammad Elsayed
Journal:  Front Neurol       Date:  2012-07-06       Impact factor: 4.003

8.  A novel rat model of blast-induced traumatic brain injury simulating different damage degree: implications for morphological, neurological, and biomarker changes.

Authors:  Mengdong Liu; Chi Zhang; Wenbo Liu; Peng Luo; Lei Zhang; Yuan Wang; Zhanjiang Wang; Zhou Fei
Journal:  Front Cell Neurosci       Date:  2015-05-01       Impact factor: 5.505

Review 9.  Effects of low-level blast exposure on the nervous system: is there really a controversy?

Authors:  Gregory A Elder; James R Stone; Stephen T Ahlers
Journal:  Front Neurol       Date:  2014-12-19       Impact factor: 4.003

10.  Selective vulnerability of the cerebral vasculature to blast injury in a rat model of mild traumatic brain injury.

Authors:  Miguel A Gama Sosa; Rita De Gasperi; Pierce L Janssen; Frank J Yuk; Pamela C Anazodo; Paul E Pricop; Alejandro J Paulino; Bridget Wicinski; Michael C Shaughness; Eric Maudlin-Jeronimo; Aaron A Hall; Dara L Dickstein; Richard M McCarron; Mikulas Chavko; Patrick R Hof; Stephen T Ahlers; Gregory A Elder
Journal:  Acta Neuropathol Commun       Date:  2014-06-17       Impact factor: 7.801

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