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Literature DB >> 18371464

Antiplatelet drug nonresponsiveness.

Patrick Gladding¹, Mark Webster, John Ormiston, Sarah Olsen, Harvey White.

Abstract

The response to most medication, including antiplatelet drugs, is highly variable between individuals. Observational studies have shown that nonresponders to antiplatelet agents appear to have an increased incidence of vascular events. This review article reviews the background, mechanisms, and evidence in support of the clinical significance of this phenomenon.

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Year: 2008 PMID： 18371464 DOI： 10.1016/j.ahj.2007.12.034

Source DB: PubMed Journal: Am Heart J ISSN： 0002-8703 Impact factor: 4.749

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Cited

11 in total

Review 1. Antithrombotic therapy for the CardioWest temporary total artificial heart.

Authors: Christopher R Ensor; William D Cahoon; Michael A Crouch; Gundars J Katlaps; Michael L Hess; Richard H Cooke; Kyle J Gunnerson; Vigneshwar Kasirajan
Journal: Tex Heart Inst J Date: 2010

2. Cytochrome P450 2C19 polymorphism is associated with poor clinical outcomes in coronary artery disease patients treated with clopidogrel.

Authors: Bo Jin; Huan-Chun Ni; Wei Shen; Jian Li; Hai-Ming Shi; Yong Li
Journal: Mol Biol Rep Date: 2010-09-16 Impact factor: 2.316

Review 3. Antiplatelet resistance in stroke.

Authors: Mehmet Akif Topçuoglu; Ethem Murat Arsava; Hakan Ay
Journal: Expert Rev Neurother Date: 2011-02 Impact factor: 4.618

4. Effect of 450-mg loading dose of clopidogrel on platelet function in Japanese patients undergoing coronary stent placement.

Authors: Kenichi Fukushima; Yoshio Kobayashi; Hideki Kitahara; Yo Iwata; Nakabumi Kuroda; Masayuki Ooyama; Fumio Nomura; Issei Komuro
Journal: Heart Vessels Date: 2010-05-29 Impact factor: 2.037

5. Microfludic platforms for the evaluation of anti-platelet agent efficacy under hyper-shear conditions associated with ventricular assist devices.

Authors: Annalisa Dimasi; Marco Rasponi; Filippo Consolo; Gianfranco B Fiore; Danny Bluestein; Marvin J Slepian; Alberto Redaelli
Journal: Med Eng Phys Date: 2017-08-30 Impact factor: 2.242

Antiplatelet drug nonresponsiveness.

Review 1. Antithrombotic therapy for the CardioWest temporary total artificial heart.

2. Cytochrome P450 2C19 polymorphism is associated with poor clinical outcomes in coronary artery disease patients treated with clopidogrel.

Review 3. Antiplatelet resistance in stroke.

4. Effect of 450-mg loading dose of clopidogrel on platelet function in Japanese patients undergoing coronary stent placement.

5. Microfludic platforms for the evaluation of anti-platelet agent efficacy under hyper-shear conditions associated with ventricular assist devices.

Review 6. Acute coronary syndromes: advances in antithrombotics.

Review 7. [Perioperative management of patients with coronary stents in non-cardiac surgery].

8. Anti-platelet Therapy Resistance - Concept, Mechanisms and Platelet Function Tests in Intensive Care Facilities.

9. P2Y12 Receptor Inhibitors in Acute Coronary Syndromes: What Is New on the Horizon?

10. Targeted thrombolysis strategies for neuroprotective effect.