Literature DB >> 18371376

Sic transit gloria: farewell to the epidermal transit amplifying cell?

Philip H Jones1, Benjamin D Simons, Fiona M Watt.   

Abstract

For the past 30 years, the prevailing model of epidermal homeostasis has been that epidermal stem cells give rise to transit amplifying cells, which undergo a limited number of cell divisions before initiating terminal differentiation. Recent studies challenge the existence of a transit amplifying cell compartment and suggest a new paradigm for epidermal homeostasis.

Mesh：

Year:  2007        PMID： 18371376     DOI： 10.1016/j.stem.2007.09.014

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  79 in total

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