Literature DB >> 18371325

Stem cells and the rate of living.

Janakiraman Krishnamurthy1, Norman E Sharpless.   

Abstract

The "rate-of-living theory" is an ancient explanation of longevity which holds that aging occurs due to the exhaustion of some finite substance-breaths, heartbeats, etc. While this theory as originally conceived has been debunked, new work (Ruzankina et al. [2007], in this issue of Cell Stem Cell) suggests that mammals in fact do have a finite number of stem cell replications per life.

Mesh:

Year:  2007        PMID: 18371325     DOI: 10.1016/j.stem.2007.05.004

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  9 in total

1.  Role of sirtuins in stem cell differentiation.

Authors:  R M Rodriguez; A F Fernandez; M F Fraga
Journal:  Genes Cancer       Date:  2013-03

Review 2.  Replicative stress, stem cells and aging.

Authors:  Yaroslava Ruzankina; Amma Asare; Eric J Brown
Journal:  Mech Ageing Dev       Date:  2008-03-28       Impact factor: 5.432

Review 3.  Insulin signaling and life span.

Authors:  Angelo Avogaro; Saula Vigili de Kreutzenberg; Gian Paolo Fadini
Journal:  Pflugers Arch       Date:  2009-09-13       Impact factor: 3.657

4.  Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion.

Authors:  Miguel Ganuza; Cristina Sáiz-Ladera; Marta Cañamero; Gonzalo Gómez; Ralph Schneider; María A Blasco; David Pisano; Jesús M Paramio; David Santamaría; Mariano Barbacid
Journal:  EMBO J       Date:  2012-04-13       Impact factor: 11.598

Review 5.  Current and Future Perspectives of Stem Cell Therapy in Dermatology.

Authors:  Christine M Prodinger; Julia Reichelt; Johann W Bauer; Martin Laimer
Journal:  Ann Dermatol       Date:  2017-10-30       Impact factor: 1.444

6.  A p53-dependent response limits epidermal stem cell functionality and organismal size in mice with short telomeres.

Authors:  Ignacio Flores; Maria A Blasco
Journal:  PLoS One       Date:  2009-03-19       Impact factor: 3.240

Review 7.  The haemopoietic stem cell: between apoptosis and self renewal.

Authors:  Faris Q Alenzi; Badi Q Alenazi; Shamweel Y Ahmad; Mohamed L Salem; Ali A Al-Jabri; Richard K H Wyse
Journal:  Yale J Biol Med       Date:  2009-03

Review 8.  DNA damage, cellular senescence and organismal ageing: causal or correlative?

Authors:  Jian-Hua Chen; C Nicholes Hales; Susan E Ozanne
Journal:  Nucleic Acids Res       Date:  2007-10-02       Impact factor: 16.971

Review 9.  Relationships between stem cell exhaustion, tumour suppression and ageing.

Authors:  Y Ruzankina; E J Brown
Journal:  Br J Cancer       Date:  2007-10-09       Impact factor: 7.640

  9 in total

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