Literature DB >> 24020001

Role of sirtuins in stem cell differentiation.

R M Rodriguez1, A F Fernandez, M F Fraga.   

Abstract

Sirtuins play an essential role in the cellular response to environmental stress, promoting DNA repair, telomere stability, cell cycle arrest, cellular senescence, and apoptosis. Much attention has been given to the role of sirtuins in aging and cancer development; however, less is known about their role in stem cell regulation. This review focuses in this topic and discusses the possible implications in adult stem cell aging.

Entities:  

Keywords:  aging; development; sirtuins; stem cells

Year:  2013        PMID： 24020001      PMCID： PMC3764466          DOI： 10.1177/1947601913479798

Source DB:  PubMed          Journal:  Genes Cancer        ISSN： 1947-6019


  97 in total

1.  Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle.

Authors:  Sylvia C Dryden; Fatimah A Nahhas; James E Nowak; Anton-Scott Goustin; Michael A Tainsky
Journal:  Mol Cell Biol       Date:  2003-05       Impact factor: 4.272

2.  Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.

Authors:  Raul Mostoslavsky; Katrin F Chua; David B Lombard; Wendy W Pang; Miriam R Fischer; Lionel Gellon; Pingfang Liu; Gustavo Mostoslavsky; Sonia Franco; Michael M Murphy; Kevin D Mills; Parin Patel; Joyce T Hsu; Andrew L Hong; Ethan Ford; Hwei-Ling Cheng; Caitlin Kennedy; Nomeli Nunez; Roderick Bronson; David Frendewey; Wojtek Auerbach; David Valenzuela; Margaret Karow; Michael O Hottiger; Stephen Hursting; J Carl Barrett; Leonard Guarente; Richard Mulligan; Bruce Demple; George D Yancopoulos; Frederick W Alt
Journal:  Cell       Date:  2006-01-27       Impact factor: 41.582

3.  SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity.

Authors:  Hyun-Seok Kim; Athanassios Vassilopoulos; Rui-Hong Wang; Tyler Lahusen; Zhen Xiao; Xiaoling Xu; Cuiling Li; Timothy D Veenstra; Bing Li; Hongtao Yu; Junfang Ji; Xin Wei Wang; Seong-Hoon Park; Yong I Cha; David Gius; Chu-Xia Deng
Journal:  Cancer Cell       Date:  2011-10-18       Impact factor: 31.743

Review 4.  NF-κB in immunobiology.

Authors:  Matthew S Hayden; Sankar Ghosh
Journal:  Cell Res       Date:  2011-01-18       Impact factor: 25.617

5.  DNA methyltransferases control telomere length and telomere recombination in mammalian cells.

Authors:  Susana Gonzalo; Isabel Jaco; Mario F Fraga; Taiping Chen; En Li; Manel Esteller; María A Blasco
Journal:  Nat Cell Biol       Date:  2006-03-26       Impact factor: 28.824

6.  SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310.

Authors:  Karin M Rothgiesser; Süheda Erener; Susanne Waibel; Bernhard Lüscher; Michael O Hottiger
Journal:  J Cell Sci       Date:  2010-11-16       Impact factor: 5.285

7.  The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms.

Authors:  M Kaeberlein; M McVey; L Guarente
Journal:  Genes Dev       Date:  1999-10-01       Impact factor: 11.361

8.  The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability.

Authors:  Bo Yang; Bernadette M M Zwaans; Mark Eckersdorff; David B Lombard
Journal:  Cell Cycle       Date:  2009-08-22       Impact factor: 4.534

9.  Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state.

Authors:  Marcella Fulco; R Louis Schiltz; Simona Iezzi; M Todd King; Po Zhao; Yoshihiro Kashiwaya; Eric Hoffman; Richard L Veech; Vittorio Sartorelli
Journal:  Mol Cell       Date:  2003-07       Impact factor: 17.970

10.  Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice.

Authors:  Rui-Hong Wang; Kundan Sengupta; Cuiling Li; Hyun-Seok Kim; Liu Cao; Cuiying Xiao; Sangsoo Kim; Xiaoling Xu; Yin Zheng; Beverly Chilton; Rong Jia; Zhi-Ming Zheng; Ettore Appella; Xin Wei Wang; Thomas Ried; Chu-Xia Deng
Journal:  Cancer Cell       Date:  2008-10-07       Impact factor: 31.743
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  15 in total

1.  Effect of vitrification on global gene expression dynamics of bovine elongating embryos.

Authors:  Emilio Gutierrez-Castillo; Hao Ming; Brittany Foster; Lauren Gatenby; Chun Kuen Mak; Carlos Pinto; Kenneth Bondioli; Zongliang Jiang
Journal:  Reprod Fertil Dev       Date:  2021-03       Impact factor: 2.311

2.  Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model.

Authors:  Ali Sohail Farooqi; Jun Young Hong; Ji Cao; Xuan Lu; Ian Robert Price; Qingjie Zhao; Tatsiana Kosciuk; Min Yang; Jessica Jingyi Bai; Hening Lin
Journal:  J Med Chem       Date:  2019-04-15       Impact factor: 7.446

Review 3.  Mitochondrial respiratory quiescence: A new model for examining the role of mitochondrial metabolism in development.

Authors:  Helin Hocaoglu; Matthew Sieber
Journal:  Semin Cell Dev Biol       Date:  2022-04-18       Impact factor: 7.499

4.  Whole blood transcriptional profiling reveals deregulation of oxidative and antioxidative defence genes in myelofibrosis and related neoplasms. Potential implications of downregulation of Nrf2 for genomic instability and disease progression.

Authors:  Hans Carl Hasselbalch; Mads Thomassen; Caroline Hasselbalch Riley; Lasse Kjær; Thomas Stauffer Larsen; Morten K Jensen; Ole Weis Bjerrum; Torben A Kruse; Vibe Skov
Journal:  PLoS One       Date:  2014-11-14       Impact factor: 3.240

5.  Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury.

Authors:  Beata Jablonska; Marcin Gierdalski; Li-Jin Chew; Teresa Hawley; Mackenzie Catron; Arturo Lichauco; Juan Cabrera-Luque; Tracy Yuen; David Rowitch; Vittorio Gallo
Journal:  Nat Commun       Date:  2016-12-19       Impact factor: 14.919

6.  Upregulation of mitochondrial NAD+ levels impairs the clonogenicity of SSEA1+ glioblastoma tumor-initiating cells.

Authors:  Myung Jin Son; Jae-Sung Ryu; Jae Yun Kim; Youjeong Kwon; Kyung-Sook Chung; Seon Ju Mun; Yee Sook Cho
Journal:  Exp Mol Med       Date:  2017-06-09       Impact factor: 8.718

7.  A potent and selective small molecule inhibitor of sirtuin 1 promotes differentiation of pluripotent P19 cells into functional neurons.

Authors:  Beom Seok Kim; Chang-Hee Lee; Gyeong-Eon Chang; Eunji Cheong; Injae Shin
Journal:  Sci Rep       Date:  2016-09-29       Impact factor: 4.379

8.  Rapamycin ameliorates chitosan nanoparticle-induced developmental defects of preimplantation embryos in mice.

Authors:  Yun-Jung Choi; Sangiliyandi Gurunathan; DaSom Kim; Hyung Seok Jang; Woo-Jin Park; Ssang-Goo Cho; Chankyu Park; Hyuk Song; Han Geuk Seo; Jin-Hoi Kim
Journal:  Oncotarget       Date:  2016-11-15

9.  Per2 Upregulation in Circulating Hematopoietic Progenitor Cells During Chronic HIV Infection.

Authors:  Veronica Bordoni; Eleonora Tartaglia; Giulia Refolo; Alessandra Sacchi; Germana Grassi; Andrea Antinori; Gian Maria Fimia; Chiara Agrati
Journal:  Front Cell Infect Microbiol       Date:  2020-07-21       Impact factor: 5.293

10.  A new SIRT1 inhibitor, MHY2245, induces autophagy and inhibits energy metabolism via PKM2/mTOR pathway in human ovarian cancer cells.

Authors:  In Hwan Tae; Ji Yeon Son; Su Hyun Lee; Mi-Young Ahn; Kyungsil Yoon; Sungpil Yoon; Hyung Ryong Moon; Hyung Sik Kim
Journal:  Int J Biol Sci       Date:  2020-04-06       Impact factor: 6.580
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