Literature DB >> 18365661

Targeting glycoproteins or glycolipids and their metabolic pathways for antiparasite therapy.

Sumi Mukhopadhyay nee Bandyopadhyay1, Chitra Mandal.   

Abstract

Carbohydrate-based therapy, known as glycotherapeutics, is a new and emerging field that promises to be the future hope for combating kinetoplastid infections more efficiently and effectively. Targeting novel glycoproteins/lipids, which are important disease determinants of kinetoplastid diseases, have helped in the development of this field. Better and refined understanding of all the available data would possibly help us in providing a future direction for rational drug design and better disease management. This review intends to focus on such lines, which will give us an insight into the future hope for development of novel therapeutic strategies through glycobiological platform for combating kinetoplastid infections.

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Year:  2008        PMID: 18365661     DOI: 10.1007/978-0-387-77570-8_8

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  5 in total

Review 1.  The Role of Sialic Acids in the Establishment of Infections by Pathogens, With Special Focus on Leishmania.

Authors:  Tainá Cavalcante; Mariana Medina Medeiros; Simon Ngao Mule; Giuseppe Palmisano; Beatriz Simonsen Stolf
Journal:  Front Cell Infect Microbiol       Date:  2021-05-13       Impact factor: 5.293

2.  Glycosylation of erythrocyte spectrin and its modification in visceral leishmaniasis.

Authors:  Sajal Samanta; Devawati Dutta; Angana Ghoshal; Sumi Mukhopadhyay; Bibhuti Saha; Shyam Sundar; Saulius Jarmalavicius; Michael Forgber; Chhabinath Mandal; Peter Walden; Chitra Mandal
Journal:  PLoS One       Date:  2011-12-02       Impact factor: 3.240

3.  Glycoproteins in circulating immune complexes are biomarkers of patients with Indian PKDL: A study from endemic districts of West Bengal, India.

Authors:  Priyank Jaiswal; Souvik Datta; Bikash Sardar; Surya Jyoti Chaudhuri; Dipankar Maji; Manab Ghosh; Bibhuti Saha; Sumi Mukhopadhyay
Journal:  PLoS One       Date:  2018-02-08       Impact factor: 3.240

Review 4.  Sialic acids siglec interaction: a unique strategy to circumvent innate immune response by pathogens.

Authors:  Biswajit Khatua; Saptarshi Roy; Chitra Mandal
Journal:  Indian J Med Res       Date:  2013-11       Impact factor: 2.375

5.  Leishmania donovani Utilize Sialic Acids for Binding and Phagocytosis in the Macrophages through Selective Utilization of Siglecs and Impair the Innate Immune Arm.

Authors:  Saptarshi Roy; Chitra Mandal
Journal:  PLoS Negl Trop Dis       Date:  2016-08-05
  5 in total

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