Literature DB >> 18355716

Structural studies of RNA/DNA polypurine tracts.

Megan E Fitzgerald1, Alexander C Drohat.   

Abstract

During reverse transcription, an RNA polypurine tract (PPT) resists digestion by reverse transcriptase (RT) and primes plus-strand DNA synthesis. In this issue of Chemistry & Biology, Yi-Brunozzi et al. (2008) report structural studies of PPTs, illuminating how they are recognized by RT.

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Year:  2008        PMID： 18355716      PMCID： PMC2828867          DOI： 10.1016/j.chembiol.2008.03.001

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  9 in total

Review 1.  Replacing the nucleobases in DNA with designer molecules.

Authors:  Eric T Kool
Journal:  Acc Chem Res       Date:  2002-11       Impact factor: 22.384

2.  A ribose sugar conformational switch in the LTR-retrotransposon Ty3 polypurine tract-containing RNA/DNA hybrid.

Authors:  Hye Young Yi-Brunozzi; Danielle M Brabazon; Daniela Lener; Stuart F J Le Grice; John P Marino
Journal:  J Am Chem Soc       Date:  2005-11-30       Impact factor: 15.419

3.  Solution structure of r(gaggacug):d(CAGTCCTC) hybrid: implications for the initiation of HIV-1 (+)-strand synthesis.

Authors:  O Y Fedoroff; Y Ge; B R Reid
Journal:  J Mol Biol       Date:  1997-06-06       Impact factor: 5.469

4.  Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA.

Authors:  S G Sarafianos; K Das; C Tantillo; A D Clark; J Ding; J M Whitcomb; P L Boyer; S H Hughes; E Arnold
Journal:  EMBO J       Date:  2001-03-15       Impact factor: 11.598

5.  Pre-existing distortions in nucleic acid structure aid polypurine tract selection by HIV-1 reverse transcriptase.

Authors:  Mamuka Kvaratskhelia; Scott R Budihas; Stuart F J Le Grice
Journal:  J Biol Chem       Date:  2002-03-01       Impact factor: 5.157

6.  High-resolution NMR analysis of the conformations of native and base analog substituted retroviral and LTR-retrotransposon PPT primers.

Authors:  Hye Young Yi-Brunozzi; Robert G Brinson; Danielle M Brabazon; Daniela Lener; Stuart F J Le Grice; John P Marino
Journal:  Chem Biol       Date:  2008-03

7.  Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3' polypurine tract.

Authors:  Chandravanu Dash; Jason W Rausch; Stuart F J Le Grice
Journal:  Nucleic Acids Res       Date:  2004-03-05       Impact factor: 16.971

8.  An unusual sugar conformation in the structure of an RNA/DNA decamer of the polypurine tract may affect recognition by RNase H.

Authors:  Mary L Kopka; Laurence Lavelle; Gye Won Han; Ho-Leung Ng; Richard E Dickerson
Journal:  J Mol Biol       Date:  2003-12-05       Impact factor: 5.469

Review 9.  'Binding, bending and bonding': polypurine tract-primed initiation of plus-strand DNA synthesis in human immunodeficiency virus.

Authors:  Jason W Rausch; Stuart F J Le Grice
Journal:  Int J Biochem Cell Biol       Date:  2004-09       Impact factor: 5.085
  9 in total
  1 in total

Review 1.  Come-back of phenanthridine and phenanthridinium derivatives in the 21st century.

Authors:  Lidija-Marija Tumir; Marijana Radić Stojković; Ivo Piantanida
Journal:  Beilstein J Org Chem       Date:  2014-12-10       Impact factor: 2.883
  1 in total

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