BACKGROUND: Few data are available on the incidence, risk factors and contamination pathways involved in acute indigenous hepatitis E in developed countries. AIMS: To draw up an overall picture of hepatitis E cases, to confirm whether or not the majority of the cases were indigenous and to attempt to identify the risk factors and contamination pathways involved in hepatitis E. METHODS: This study was performed in the framework of a national network (ANGH) including 96 participating centres. The 19 centres with at least one case of acute HEV reported a total number of 53 cases. RESULTS: A decreasing South-to-North geographic gradient was observed. A nonspecific clinical profile was observed in many cases. Acute hepatitis E was of indigenous origin in 90% of the patients. The most relevant and/or frequent possible risk factors among the 47 indigenous metropolitan cases were water consumption from a personal water supply, uncooked shellfish consumption and the recent acquisition of a pet pig. CONCLUSIONS: This national survey confirmed that acute indigenous hepatitis E is an emerging disease in developed countries such as France, and suggests that various risk factors are responsible for acute indigenous hepatitis E contamination in non-endemic countries.
BACKGROUND: Few data are available on the incidence, risk factors and contamination pathways involved in acute indigenous hepatitis E in developed countries. AIMS: To draw up an overall picture of hepatitis E cases, to confirm whether or not the majority of the cases were indigenous and to attempt to identify the risk factors and contamination pathways involved in hepatitis E. METHODS: This study was performed in the framework of a national network (ANGH) including 96 participating centres. The 19 centres with at least one case of acute HEV reported a total number of 53 cases. RESULTS: A decreasing South-to-North geographic gradient was observed. A nonspecific clinical profile was observed in many cases. Acute hepatitis E was of indigenous origin in 90% of the patients. The most relevant and/or frequent possible risk factors among the 47 indigenous metropolitan cases were water consumption from a personal water supply, uncooked shellfish consumption and the recent acquisition of a pet pig. CONCLUSIONS: This national survey confirmed that acute indigenous hepatitis E is an emerging disease in developed countries such as France, and suggests that various risk factors are responsible for acute indigenous hepatitis E contamination in non-endemic countries.
Authors: G La Rosa; Y T R Proroga; D De Medici; F Capuano; M Iaconelli; S Della Libera; E Suffredini Journal: Food Environ Virol Date: 2017-09-27 Impact factor: 2.778
Authors: P Kokkinos; I Kozyra; S Lazic; M Bouwknegt; S Rutjes; K Willems; R Moloney; A M de Roda Husman; A Kaupke; E Legaki; M D'Agostino; N Cook; A Rzeżutka; T Petrovic; A Vantarakis Journal: Food Environ Virol Date: 2012-09-21 Impact factor: 2.778
Authors: Andi Krumbholz; Sebastian Joel; Paul Dremsek; Anne Neubert; Reimar Johne; Ralf Dürrwald; Mario Walther; Thomas H Müller; Detlef Kühnel; Jeannette Lange; Peter Wutzler; Andreas Sauerbrei; Rainer G Ulrich; Roland Zell Journal: Med Microbiol Immunol Date: 2014-04-18 Impact factor: 3.402
Authors: Jean Philippe Loly; Estelle Rikir; Maxime Seivert; Emile Legros; Pierre Defrance; Jacques Belaiche; Gustave Moonen; Jean Delwaide Journal: World J Gastroenterol Date: 2009-04-07 Impact factor: 5.742