David Mataix-Cols1, Eriko Nakatani2, Nadia Micali2, Isobel Heyman2. 1. The authors are with King's College London, Institute of Psychiatry. Electronic address: d.mataix@iop.kcl.ac.uk. 2. The authors are with King's College London, Institute of Psychiatry.
Abstract
OBJECTIVE: It is unclear whether the structure of obsessive-compulsive disorder (OCD) symptoms seen in adults is preserved in pediatric samples. METHOD: A total of 238 children and adolescents referred to a specialty pediatric OCD clinic were administered the Children's Yale-Brown Obsessive Compulsive Scale Symptom Checklist, and its 13 major symptom categories were subjected to exploratory principal components analysis. The resulting factors were correlated with relevant clinical variables. RESULTS: Principal components analysis identified four symptom dimensions explaining 55% of the total variance and broadly corresponding to those seen in adult samples. Boys were more likely to have sexual obsessions (34% vs. 18%, p = .01), whereas girls were more likely to endorse hoarding compulsions (53% vs. 36%, p=.009). High scores on the hoarding dimension were associated with increased levels of pervasive slowness, responsibility, indecisiveness, pathological doubt, depression and a variety of emotional difficulties, both self-rated and parent-rated. CONCLUSIONS: The structure of OCD symptoms is similar across the lifespan. Hoarding symptoms are prevalent in pediatric OCD, especially among girls, and are associated with greater levels of disability.
OBJECTIVE: It is unclear whether the structure of obsessive-compulsive disorder (OCD) symptoms seen in adults is preserved in pediatric samples. METHOD: A total of 238 children and adolescents referred to a specialty pediatric OCD clinic were administered the Children's Yale-Brown Obsessive Compulsive Scale Symptom Checklist, and its 13 major symptom categories were subjected to exploratory principal components analysis. The resulting factors were correlated with relevant clinical variables. RESULTS: Principal components analysis identified four symptom dimensions explaining 55% of the total variance and broadly corresponding to those seen in adult samples. Boys were more likely to have sexual obsessions (34% vs. 18%, p = .01), whereas girls were more likely to endorse hoarding compulsions (53% vs. 36%, p=.009). High scores on the hoarding dimension were associated with increased levels of pervasive slowness, responsibility, indecisiveness, pathological doubt, depression and a variety of emotional difficulties, both self-rated and parent-rated. CONCLUSIONS: The structure of OCD symptoms is similar across the lifespan. Hoarding symptoms are prevalent in pediatric OCD, especially among girls, and are associated with greater levels of disability.
Authors: Eric A Storch; Regina Bussing; Marni L Jacob; Joshua M Nadeau; Erika Crawford; P Jane Mutch; Dana Mason; Adam B Lewin; Tanya K Murphy Journal: Child Psychiatry Hum Dev Date: 2015-02
Authors: Fabian Lenhard; Sebastian Sauer; Erik Andersson; Kristoffer Nt Månsson; David Mataix-Cols; Christian Rück; Eva Serlachius Journal: Int J Methods Psychiatr Res Date: 2017-07-28 Impact factor: 4.035
Authors: Hilga Katerberg; Kevin L Delucchi; S Evelyn Stewart; Christine Lochner; Damiaan A J P Denys; Denise E Stack; J Michael Andresen; J E Grant; Suck W Kim; Kyle A Williams; Johan A den Boer; Anton J L M van Balkom; Johannes H Smit; Patricia van Oppen; Annemiek Polman; Michael A Jenike; Dan J Stein; Carol A Mathews; Danielle C Cath Journal: Behav Genet Date: 2010-04-02 Impact factor: 2.805