Literature DB >> 18344367

Evidence that AphB, essential for the virulence of Vibrio vulnificus, is a global regulator.

Hee Gon Jeong1, Sang Ho Choi.   

Abstract

The Vibrio vulnificus aphB mutant was significantly less virulent than the wild type and was impaired in motility and adherence to host cells. Microarray analysis revealed that AphB of V. vulnificus (AphB(Vv)) influences the expression of over 10% of the V. vulnificus genome. The combined results indicated that AphB(Vv) is a global regulator contributing to the pathogenesis of V. vulnificus.

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Year:  2008        PMID： 18344367      PMCID： PMC2395019          DOI： 10.1128/JB.00058-08

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  31 in total

1.  Binding site requirements of the virulence gene regulator AphB: differential affinities for the Vibrio cholerae classical and El Tor tcpPH promoters.

Authors:  Gabriela Kovacikova; Karen Skorupski
Journal:  Mol Microbiol       Date:  2002-04       Impact factor: 3.501

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3.  Regulatory cascade controls virulence in Vibrio cholerae.

Authors:  V J DiRita; C Parsot; G Jander; J J Mekalanos
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-15       Impact factor: 11.205

4.  Production of extracellular enzymes and cytotoxicity by Vibrio vulnificus.

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Journal:  Diagn Microbiol Infect Dis       Date:  1986-07       Impact factor: 2.803

5.  Overlapping binding sites for the virulence gene regulators AphA, AphB and cAMP-CRP at the Vibrio cholerae tcpPH promoter.

Authors:  G Kovacikova; K Skorupski
Journal:  Mol Microbiol       Date:  2001-07       Impact factor: 3.501

6.  Identification of the cadBA operon from Vibrio vulnificus and its influence on survival to acid stress.

Authors:  Jee Eun Rhee; Joon Haeng Rhee; Phil Youl Ryu; Sang Ho Choi
Journal:  FEMS Microbiol Lett       Date:  2002-03-05       Impact factor: 2.742

7.  TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae.

Authors:  C C Häse; J J Mekalanos
Journal:  Proc Natl Acad Sci U S A       Date:  1998-01-20       Impact factor: 11.205

8.  Cloning of the cytotoxin-hemolysin gene of Vibrio vulnificus.

Authors:  A C Wright; J G Morris; D R Maneval; K Richardson; J B Kaper
Journal:  Infect Immun       Date:  1985-12       Impact factor: 3.441

Review 9.  Cyclic di-GMP as a bacterial second messenger.

Authors:  David A D'Argenio; Samuel I Miller
Journal:  Microbiology (Reading)       Date:  2004-08       Impact factor: 2.777

10.  Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans.

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Journal:  J Exp Med       Date:  1988-10-01       Impact factor: 14.307
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  15 in total

1.  Vibrio cholerae anaerobic induction of virulence gene expression is controlled by thiol-based switches of virulence regulator AphB.

Authors:  Zhi Liu; Menghua Yang; Gregory L Peterfreund; Amy M Tsou; Nur Selamoglu; Fevzi Daldal; Zengtao Zhong; Biao Kan; Jun Zhu
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-27       Impact factor: 11.205

Review 2.  Vibrio vulnificus: disease and pathogenesis.

Authors:  Melissa K Jones; James D Oliver
Journal:  Infect Immun       Date:  2009-03-02       Impact factor: 3.441

3.  Identification of the Regulon of AphB and Its Essential Roles in LuxR and Exotoxin Asp Expression in the Pathogen Vibrio alginolyticus.

Authors:  Xiating Gao; Yang Liu; Huan Liu; Zhen Yang; Qin Liu; Yuanxing Zhang; Qiyao Wang
Journal:  J Bacteriol       Date:  2017-09-19       Impact factor: 3.490

4.  The LysR-type virulence activator AphB regulates the expression of genes in Vibrio cholerae in response to low pH and anaerobiosis.

Authors:  Gabriela Kovacikova; Wei Lin; Karen Skorupski
Journal:  J Bacteriol       Date:  2010-06-18       Impact factor: 3.490

5.  Comparative genomics of the family Vibrionaceae reveals the wide distribution of genes encoding virulence-associated proteins.

Authors:  Timothy G Lilburn; Jianying Gu; Hong Cai; Yufeng Wang
Journal:  BMC Genomics       Date:  2010-06-10       Impact factor: 3.969

6.  Identification and characterization of Vibrio vulnificus plpA encoding a phospholipase A2 essential for pathogenesis.

Authors:  Kyung Ku Jang; Zee-Won Lee; Bityeoul Kim; Young Hyun Jung; Ho Jae Han; Myung Hee Kim; Byoung Sik Kim; Sang Ho Choi
Journal:  J Biol Chem       Date:  2017-08-30       Impact factor: 5.157

7.  A consensus sequence for binding of SmcR, a Vibrio vulnificus LuxR homologue, and genome-wide identification of the SmcR regulon.

Authors:  Dong Hwan Lee; Hye Sook Jeong; Hee Gon Jeong; Kyung Mo Kim; Heebal Kim; Sang Ho Choi
Journal:  J Biol Chem       Date:  2008-06-25       Impact factor: 5.157

8.  Regulation of the Vibrio vulnificus hupA gene by temperature alteration and cyclic AMP receptor protein and evaluation of its role in virulence.

Authors:  Man Hwan Oh; Sung Min Lee; Dong Hwan Lee; Sang Ho Choi
Journal:  Infect Immun       Date:  2009-01-12       Impact factor: 3.441

9.  Identification of the Vibrio vulnificus ahpCl gene and its influence on survival under oxidative stress and virulence.

Authors:  Woon Ki Baek; Hyun Sung Lee; Man Hwan Oh; Myung Jin Koh; Kun-Soo Kim; Sang Ho Choi
Journal:  J Microbiol       Date:  2009-10-24       Impact factor: 3.422

10.  IscR is a global regulator essential for pathogenesis of Vibrio vulnificus and induced by host cells.

Authors:  Jong Gyu Lim; Sang Ho Choi
Journal:  Infect Immun       Date:  2013-11-18       Impact factor: 3.441
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