Literature DB >> 18344027

Pathophysiology of myocardial infarction: protection by ischemic pre- and postconditioning.

Andreas Skyschally1, Rainer Schulz, Gerd Heusch.   

Abstract

One or several short cycles of ischemia/reperfusion before (preconditioning) or after (postconditioning) a sustained coronary occlusion with subsequent reperfusion reduce the ultimate infarct size. The protection is potent, but limited to a narrow time frame. In animal experiments, a complex signal transduction cascade was identified which results specifically in a reduction of reperfusion injury. There is evidence for both ischemic pre- and postconditioning in patients with coronary artery disease.

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Year:  2008        PMID： 18344027     DOI： 10.1007/s00059-008-3101-9

Source DB:  PubMed          Journal:  Herz        ISSN： 0340-9937            Impact factor:   1.443


  29 in total

1.  Mitochondrial permeability transition triggers the release of mtDNA fragments.

Authors:  M Patrushev; V Kasymov; V Patrusheva; T Ushakova; V Gogvadze; A Gaziev
Journal:  Cell Mol Life Sci       Date:  2004-12       Impact factor: 9.261

Review 2.  Regulation and pharmacology of the mitochondrial permeability transition pore.

Authors:  Dmitry B Zorov; Magdalena Juhaszova; Yael Yaniv; H Bradley Nuss; Su Wang; Steven J Sollott
Journal:  Cardiovasc Res       Date:  2009-05-15       Impact factor: 10.787

Review 3.  Mitochondrial calcium and the regulation of metabolism in the heart.

Authors:  George S B Williams; Liron Boyman; W Jonathan Lederer
Journal:  J Mol Cell Cardiol       Date:  2014-11-07       Impact factor: 5.000

4.  Acute (but not chronic) smoking paradoxically protects the endothelium from ischemia and reperfusion: insight into the "smoking paradox".

Authors:  Monica Lisi; Saverio Dragoni; Maria Cristina Leone; Thomas Münzel; John D Parker; Tommaso Gori
Journal:  Clin Res Cardiol       Date:  2013-02-19       Impact factor: 5.460

Review 5.  Concepts of hypoxic NO signaling in remote ischemic preconditioning.

Authors:  Matthias Totzeck; Ulrike Hendgen-Cotta; Tienush Rassaf
Journal:  World J Cardiol       Date:  2015-10-26

6.  Cardioprotection by ischemic postconditioning is abolished in depressed rats: role of Akt and signal transducer and activator of transcription-3.

Authors:  Chuanjun Zhuo; Ying Wang; Xiaohui Wang; Yufen Wang; Yuhui Chen
Journal:  Mol Cell Biochem       Date:  2010-09-10       Impact factor: 3.396

7.  Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha.

Authors:  C A Carvajal; A A Herrada; C R Castillo; F J Contreras; C B Stehr; L M Mosso; A M Kalergis; C E Fardella
Journal:  J Endocrinol Invest       Date:  2009-10       Impact factor: 4.256

8.  Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion.

Authors:  Kerstin Boengler; Denise Hilfiker-Kleiner; Gerd Heusch; Rainer Schulz
Journal:  Basic Res Cardiol       Date:  2010-10-20       Impact factor: 17.165

Review 9.  Protective ischaemia in patients: preconditioning and postconditioning.

Authors:  Asger Granfeldt; David J Lefer; Jakob Vinten-Johansen
Journal:  Cardiovasc Res       Date:  2009-04-27       Impact factor: 10.787

10.  Apyrase treatment of myocardial infarction according to a clinically applicable protocol fails to reduce myocardial injury in a porcine model.

Authors:  Jesper van der Pals; Sasha Koul; Michael I Götberg; Göran K Olivecrona; Martin Ugander; Mikael Kanski; Andreas Otto; Matthias Götberg; Håkan Arheden; David Erlinge
Journal:  BMC Cardiovasc Disord       Date:  2010-01-04       Impact factor: 2.298
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