PURPOSE: To compare high-definition (HD) spectral-domain optical coherence tomography [SD-OCT] (Cirrus HD-OCT; Carl Zeiss, Dublin, California, USA) with time-domain optical coherence tomography [TD-OCT] (Stratus version 4; Carl Zeiss) for imaging macula in patients of uveitis. DESIGN: Interventional case series. METHODS: Thirty consecutive patients (51 eyes) with uveitis of various causes with vitreous haze of 1+ or worse were treated in an institutional setting. All patients had their vitreous haze graded and OCT scans both on TD-OCT (Stratus) and SD-OCT (Cirrus). Information obtained from Cirrus OCT scans was compared with that obtained from Stratus OCT scans. RESULTS: Overall, for all grades of media clarity, the macula was interpreted as normal in 30 eyes (58.8%) on Stratus OCT and 26 eyes (50.9%) on Cirrus OCT and abnormal in 15 eyes (29.4%) on Stratus OCT and 24 eyes (47.0%) on Cirrus OCT, whereas poor scan quality deterred any interpretation in six eyes (10.0%) on Stratus OCT and only in one eye (1.8%) on Cirrus OCT. Additional information on Cirrus OCT could be obtained in nine (21.9%) of 41 eyes with grade 1+ vitreous haze, six (75%) of eight eyes with grade 2+ vitreous haze, and one eye (50%) with vitreous haze of 3+. CONCLUSIONS: Our preliminary results suggest that SD Cirrus HD-OCT has an advantage over TD Stratus OCT in uveitic eyes by providing better identification of normal and pathologic structure in patients with poor media clarity.
PURPOSE: To compare high-definition (HD) spectral-domain optical coherence tomography [SD-OCT] (Cirrus HD-OCT; Carl Zeiss, Dublin, California, USA) with time-domain optical coherence tomography [TD-OCT] (Stratus version 4; Carl Zeiss) for imaging macula in patients of uveitis. DESIGN: Interventional case series. METHODS: Thirty consecutive patients (51 eyes) with uveitis of various causes with vitreous haze of 1+ or worse were treated in an institutional setting. All patients had their vitreous haze graded and OCT scans both on TD-OCT (Stratus) and SD-OCT (Cirrus). Information obtained from Cirrus OCT scans was compared with that obtained from Stratus OCT scans. RESULTS: Overall, for all grades of media clarity, the macula was interpreted as normal in 30 eyes (58.8%) on Stratus OCT and 26 eyes (50.9%) on Cirrus OCT and abnormal in 15 eyes (29.4%) on Stratus OCT and 24 eyes (47.0%) on Cirrus OCT, whereas poor scan quality deterred any interpretation in six eyes (10.0%) on Stratus OCT and only in one eye (1.8%) on Cirrus OCT. Additional information on Cirrus OCT could be obtained in nine (21.9%) of 41 eyes with grade 1+ vitreous haze, six (75%) of eight eyes with grade 2+ vitreous haze, and one eye (50%) with vitreous haze of 3+. CONCLUSIONS: Our preliminary results suggest that SD Cirrus HD-OCT has an advantage over TD Stratus OCT in uveitic eyes by providing better identification of normal and pathologic structure in patients with poor media clarity.
Authors: Michelle L Gabriele; Gadi Wollstein; Hiroshi Ishikawa; Larry Kagemann; Juan Xu; Lindsey S Folio; Joel S Schuman Journal: Invest Ophthalmol Vis Sci Date: 2011-04-14 Impact factor: 4.799
Authors: Melissa M Liu; Yulia Wolfson; Susan B Bressler; Diana V Do; Howard S Ying; Neil M Bressler Journal: Invest Ophthalmol Vis Sci Date: 2014-03-06 Impact factor: 4.799
Authors: Alan C Sull; Laurel N Vuong; Lori Lyn Price; Vivek J Srinivasan; Iwona Gorczynska; James G Fujimoto; Joel S Schuman; Jay S Duker Journal: Retina Date: 2010-02 Impact factor: 4.256