H Bassan1, L Berkner, C Stolovitch, A Kesler. 1. Pediatric Neurology Unit, 'Dana' Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Abstract
OBJECTIVE: To define characteristics of pediatric asymptomatic idiopathic intracranial hypertension (IIH). PATIENTS AND METHODS: We retrospectively reviewed our Neuro-Ophthalmology database (2000-2006) for all cases of symptomatic and asymptomatic pediatric IIH. RESULTS: Out of 45 IIH cases, 14 (31.1%) were asymptomatic (incidental examination). When compared with children with symptomatic IIH, asymptomatic cases were younger [5.6 (1.8-15) vs 11.0 (5-17) years, P = 0.007], had lower percentage of obesity (14.3% vs 48.4%, P = 0.046), and had male predominance (71.4% vs 38.7%, P = 0.06). Asymptomatic cases required shorter duration of acetazolamide treatment [3 (0-8), vs 6 (0-20) months, P = 0.021], and resulted in complete resolution of swollen discs. CONCLUSIONS: We speculate that asymptomatic IIH may be more common in young children and could represent a milder form or a presymptomatic phase before evolving into classic symptomatic IIH. Further studies to assess the clinical significance of asymptomatic IIH are warranted.
OBJECTIVE: To define characteristics of pediatric asymptomatic idiopathic intracranial hypertension (IIH). PATIENTS AND METHODS: We retrospectively reviewed our Neuro-Ophthalmology database (2000-2006) for all cases of symptomatic and asymptomatic pediatric IIH. RESULTS: Out of 45 IIH cases, 14 (31.1%) were asymptomatic (incidental examination). When compared with children with symptomatic IIH, asymptomatic cases were younger [5.6 (1.8-15) vs 11.0 (5-17) years, P = 0.007], had lower percentage of obesity (14.3% vs 48.4%, P = 0.046), and had male predominance (71.4% vs 38.7%, P = 0.06). Asymptomatic cases required shorter duration of acetazolamide treatment [3 (0-8), vs 6 (0-20) months, P = 0.021], and resulted in complete resolution of swollen discs. CONCLUSIONS: We speculate that asymptomatic IIH may be more common in young children and could represent a milder form or a presymptomatic phase before evolving into classic symptomatic IIH. Further studies to assess the clinical significance of asymptomatic IIH are warranted.
Authors: Claire A Sheldon; Grace L Paley; Shannon J Beres; Shana E McCormack; Grant T Liu Journal: Semin Pediatr Neurol Date: 2017-04-07 Impact factor: 1.636
Authors: Grace L Paley; Claire A Sheldon; Evanette K Burrows; Marianne R Chilutti; Grant T Liu; Shana E McCormack Journal: Am J Ophthalmol Date: 2014-11-07 Impact factor: 5.258
Authors: Claire A Sheldon; Grace L Paley; Rui Xiao; Anat Kesler; Ori Eyal; Melissa W Ko; Chantal J Boisvert; Robert A Avery; Vincenzo Salpietro; Paul H Phillips; Gena Heidary; Shana E McCormack; Grant T Liu Journal: Ophthalmology Date: 2016-09-28 Impact factor: 12.079
Authors: Daniel Tibussek; Dominik T Schneider; Nicola Vandemeulebroecke; Bernd Turowski; Martina Messing-Juenger; Peter H G M Willems; Ertan Mayatepek; Felix Distelmaier Journal: Childs Nerv Syst Date: 2009-11-10 Impact factor: 1.475