Literature DB >> 18341288

alpha-Glucosidase inhibitory activity of triterpenoids from Cichorium intybus.

Seema Zareen, M Iqbal Choudhary, M Nadeem Akhtar, Shamsun Nahar Khan.   

Abstract

Two new triterpenoids, 18alpha,19beta-20(30)-taraxasten-3beta,21alpha-diol (cichoridiol) (1) and 17-epi-methyl-6-hydroxyangolensate (intybusoloid) (2), were obtained from the methanolic extract of seeds of Cichorium intybus along with 11 known compounds, lupeol (3), friedelin (4), beta-sitosterol (5), stigmasterol (6), betulinic acid (7), betulin (8), betulinaldehyde (9), syringic acid (10), vanillic acid (11) 6,7-dihydroxycoumarin (12), and methyl-alpha-D-galactopyranoside (13). Compounds 1, 1a, and 11 showed a good alpha-glucosidase inhibitory activity.

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Year:  2008        PMID: 18341288     DOI: 10.1021/np800001v

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  11 in total

1.  Chemical and biological studies on Cichorium intybus L.

Authors:  Dinara Satmbekova; Radhakrishnan Srivedavyasasri; Yerkebulan Orazbekov; Roza Omarova; Ubaidilla Datkhayev; Samir A Ross
Journal:  Nat Prod Res       Date:  2017-06-19       Impact factor: 2.861

2.  Molecular Structure-Based Screening of the Constituents of Calotropis procera Identifies Potential Inhibitors of Diabetes Mellitus Target Alpha Glucosidase.

Authors:  Cynthia A Adinortey; Gabriel B Kwarko; Russell Koranteng; Daniel Boison; Issaka Obuaba; Michael D Wilson; Samuel K Kwofie
Journal:  Curr Issues Mol Biol       Date:  2022-02-21       Impact factor: 2.976

3.  Chemical constituents of Swertia longifolia Boiss. with α-amylase inhibitory activity.

Authors:  Soodabeh Saeidnia; Leila Ara; Homa Hajimehdipoor; Roger W Read; Sattar Arshadi; Marjan Nikan
Journal:  Res Pharm Sci       Date:  2016 Jan-Feb

4.  Characterization of α-Glucosidase Inhibitors from Clinacanthus nutans Lindau Leaves by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Simulation.

Authors:  Suganya Murugesu; Zalikha Ibrahim; Qamar-Uddin Ahmed; Nik-Idris Nik Yusoff; Bisha-Fathamah Uzir; Vikneswari Perumal; Faridah Abas; Khozirah Saari; Hesham El-Seedi; Alfi Khatib
Journal:  Molecules       Date:  2018-09-19       Impact factor: 4.411

Review 5.  Monocyclic phenolic acids; hydroxy- and polyhydroxybenzoic acids: occurrence and recent bioactivity studies.

Authors:  Shahriar Khadem; Robin J Marles
Journal:  Molecules       Date:  2010-11-08       Impact factor: 4.411

6.  Alleviating effects of lupeol on postprandial hyperglycemia in diabetic mice.

Authors:  Hyun-Ah Lee; Min-Jung Kim; Ji-Sook Han
Journal:  Toxicol Res (Camb)       Date:  2021-05-08       Impact factor: 3.524

7.  Betulinic acid reduces the complications of autoimmune diabetes on the body and kidney through effecting on inflammatory cytokines in C57BL/6 mice.

Authors:  Yaser Jafari Khataylou; Somayyeh Ahmadi Afshar; Navideh Mirzakhani
Journal:  Vet Res Forum       Date:  2021-06-15       Impact factor: 1.054

8.  Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity.

Authors:  Arnaud F Kouam; Fei Yuan; Frédéric N Njayou; Hongtao He; Roméo F Tsayem; Babayemi O Oladejo; Fuhang Song; Paul F Moundipa; George F Gao
Journal:  Front Pharmacol       Date:  2017-09-19       Impact factor: 5.810

9.  A New Taraxastane Triterpene from Euphorbia Denticulata with Cytotoxic Activity Against Prostate Cancer Cells.

Authors:  Sara Shamsabadipour; Seyed Mohammad Zarei; Mustafa Ghanadian; Seyed Abdulmajid Ayatollahi; Mohammad Reza Rahimnejad; Hojjatollah Saeedi; Mahmoud Aghaei
Journal:  Iran J Pharm Res       Date:  2018       Impact factor: 1.696

10.  Potent in Vitro α-Glucosidase Inhibition of Secondary Metabolites Derived from Dryopteris cycadina.

Authors:  Surriya Amin; Barkat Ullah; Mumtaz Ali; Abdur Rauf; Haroon Khan; Eugenio Uriarte; Eduardo Sobarzo-Sánchez
Journal:  Molecules       Date:  2019-01-24       Impact factor: 4.411

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