Literature DB >> 18339565

Modeling of asthma, COPD and cystic fibrosis in sheep.

William M Abraham1.   

Abstract

Sheep naturally allergic to Ascaris suum antigen have been used to study the pathophysiology of asthma and more recently allergic rhinitis, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The utility of the model as it relates to the study of these diseases is discussed.

Entities:  

Mesh：

Year:  2008        PMID： 18339565     DOI： 10.1016/j.pupt.2008.01.010

Source DB:  PubMed          Journal:  Pulm Pharmacol Ther        ISSN： 1094-5539            Impact factor:   3.410


  15 in total

1.  Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibition.

Authors:  Annika B M Åstrand; Martin Hemmerling; James Root; Cecilia Wingren; Jelena Pesic; Edvin Johansson; Alaina L Garland; Arunava Ghosh; Robert Tarran
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2014-10-31       Impact factor: 5.464

2.  Development of an in vivo ovine dry powder inhalation model for the evaluation of conventional and controlled release microparticles.

Authors:  Rania O Salama; Leigh Ladd; Hak-Kim Chan; Daniela Traini; Paul M Young
Journal:  AAPS J       Date:  2009-07-01       Impact factor: 4.009

3.  Electronic Cigarette Vapor with Nicotine Causes Airway Mucociliary Dysfunction Preferentially via TRPA1 Receptors.

Authors:  Samuel Chung; Nathalie Baumlin; John S Dennis; Robert Moore; Sebastian F Salathe; Phillip L Whitney; Juan Sabater; William M Abraham; Michael D Kim; Matthias Salathe
Journal:  Am J Respir Crit Care Med       Date:  2019-11-01       Impact factor: 21.405

4.  A Comparison of the Pharmacokinetics and Pulmonary Lymphatic Exposure of a Generation 4 PEGylated Dendrimer Following Intravenous and Aerosol Administration to Rats and Sheep.

Authors:  Gemma M Ryan; Robert J Bischof; Perenlei Enkhbaatar; Victoria M McLeod; Linda J Chan; Seth A Jones; David J Owen; Christopher J H Porter; Lisa M Kaminskas
Journal:  Pharm Res       Date:  2015-10-20       Impact factor: 4.200

5.  Clinical and molecular characterization of a re-established line of sheep exhibiting hemophilia A.

Authors:  C D Porada; C Sanada; C R Long; J A Wood; J Desai; N Frederick; L Millsap; C Bormann; S L Menges; C Hanna; G Flores-Foxworth; T Shin; M E Westhusin; W Liu; H Glimp; E D Zanjani; J N Lozier; V Pliska; G Stranzinger; H Joerg; D C Kraemer; G Almeida-Porada
Journal:  J Thromb Haemost       Date:  2009-11-23       Impact factor: 5.824

6.  Human respiratory syncytial virus A2 strain replicates and induces innate immune responses by respiratory epithelia of neonatal lambs.

Authors:  Alicia Olivier; Jack Gallup; Marcia M M A de Macedo; Steven M Varga; Mark Ackermann
Journal:  Int J Exp Pathol       Date:  2009-08       Impact factor: 1.925

Review 7.  Animal Models Reflecting Chronic Obstructive Pulmonary Disease and Related Respiratory Disorders: Translating Pre-Clinical Data into Clinical Relevance.

Authors:  Lloyd Tanner; Andrew Bruce Single
Journal:  J Innate Immun       Date:  2019-09-17       Impact factor: 7.349

8.  Increased mast cell density and airway responses to allergic and non-allergic stimuli in a sheep model of chronic asthma.

Authors:  Joanne Van der Velden; Donna Barker; Garry Barcham; Emmanuel Koumoundouros; Kenneth Snibson
Journal:  PLoS One       Date:  2012-05-14       Impact factor: 3.240

9.  Nebulized perflubron and carbon dioxide rapidly dilate constricted airways in an ovine model of allergic asthma.

Authors:  Tamer Y El Mays; Parichita Choudhury; Richard Leigh; Emmanuel Koumoundouros; Joanne Van der Velden; Grishma Shrestha; Cora A Pieron; John H Dennis; Francis Hy Green; Ken J Snibson
Journal:  Respir Res       Date:  2014-09-16

Review 10.  Understanding cellular mechanisms underlying airway epithelial repair: selecting the most appropriate animal models.

Authors:  B Yahaya
Journal:  ScientificWorldJournal       Date:  2012-09-23
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