PURPOSE: This study was done to compare the perfusion patterns of intrahepatic peripheral cholangiocarcinoma (IPCC) on contrast-enhanced ultrasound (CEUS) and dynamic computed tomography (CT). MATERIALS AND METHODS: We retrospectively reviewed 23 histologically proven cases of IPCC. All lesions were studied by CEUS with sulfur hexafluoride-filled microbubbles coated with a phospholipid capsule, and by dynamic CT. Contrast-enhancement patterns were evaluated in the arterial phase (CEUS 10-20 s after the injection; CT 25-30 s after the injection) and in the delayed phase (CEUS 120 s after the injection; CT>2-3 min after the injection). RESULTS: Lesions were single in 18/23 cases (78%), single with nearby satellite lesions in 1/23 (4%) cases and multifocal with distant secondary lesions in 4/23 (17%) cases. Lesion diameter was 2-5 cm in 7/23 cases (30%), 5-7 cm in 13/23 cases (57%) and >7 cm in 3/23 (13%) cases. On CEUS, lesions were hypervascular in 16/23 cases (70%). On delayed-phase CEUS, 22/23 lesions (96%) were markedly hypoechoic. CT showed that the lesions were hypovascular in the arterial phase in 15/23 cases (66%) and hypervascular in 7/23 (30%) cases; one lesion (1/23; 4%) was isovascular. On delayed-phase CT, lesions were hyperdense in 17/23 cases (74%), hypodense in 5/23 (22%) cases and isodense in 1/23 (43%) cases. CONCLUSIONS: Enhancement discrepancy between delayed-phase CEUS (hypoechogenicity) and CT (hyperdensity) is common semiological findings in the study of IPCC.
PURPOSE: This study was done to compare the perfusion patterns of intrahepatic peripheral cholangiocarcinoma (IPCC) on contrast-enhanced ultrasound (CEUS) and dynamic computed tomography (CT). MATERIALS AND METHODS: We retrospectively reviewed 23 histologically proven cases of IPCC. All lesions were studied by CEUS with sulfur hexafluoride-filled microbubbles coated with a phospholipid capsule, and by dynamic CT. Contrast-enhancement patterns were evaluated in the arterial phase (CEUS 10-20 s after the injection; CT 25-30 s after the injection) and in the delayed phase (CEUS 120 s after the injection; CT>2-3 min after the injection). RESULTS: Lesions were single in 18/23 cases (78%), single with nearby satellite lesions in 1/23 (4%) cases and multifocal with distant secondary lesions in 4/23 (17%) cases. Lesion diameter was 2-5 cm in 7/23 cases (30%), 5-7 cm in 13/23 cases (57%) and >7 cm in 3/23 (13%) cases. On CEUS, lesions were hypervascular in 16/23 cases (70%). On delayed-phase CEUS, 22/23 lesions (96%) were markedly hypoechoic. CT showed that the lesions were hypovascular in the arterial phase in 15/23 cases (66%) and hypervascular in 7/23 (30%) cases; one lesion (1/23; 4%) was isovascular. On delayed-phase CT, lesions were hyperdense in 17/23 cases (74%), hypodense in 5/23 (22%) cases and isodense in 1/23 (43%) cases. CONCLUSIONS: Enhancement discrepancy between delayed-phase CEUS (hypoechogenicity) and CT (hyperdensity) is common semiological findings in the study of IPCC.
Authors: P Soyer; D A Bluemke; R Reichle; P S Calhoun; D F Bliss; A Scherrer; E K Fishman Journal: AJR Am J Roentgenol Date: 1995-12 Impact factor: 3.959
Authors: Daniele Fresilli; Nicola Di Leo; Ombretta Martinelli; Luca Di Marzo; Patrizia Pacini; Vincenzo Dolcetti; Giovanni Del Gaudio; Fabrizio Canni; Ludovica Isabella Ricci; Corrado De Vito; Corrado Caiazzo; Raffaella Carletti; Cira Di Gioia; Iacopo Carbone; Steven B Feinstein; Carlo Catalano; Vito Cantisani Journal: Radiol Med Date: 2022-09-17 Impact factor: 6.313
Authors: E David; V Cantisani; H Grazhdani; L Di Marzo; L Venturini; F Fanelli; M Di Segni; N Di Leo; L Brunese; F Calliada; M Ciccariello; A Bottari; G Ascenti; F D'Ambrosio Journal: J Ultrasound Date: 2016-11-23
Authors: Jae Young Jang; Moon Young Kim; Soung Won Jeong; Tae Yeob Kim; Seung Up Kim; Sae Hwan Lee; Ki Tae Suk; Soo Young Park; Hyun Young Woo; Sang Gyune Kim; Jeong Heo; Soon Koo Baik; Hong Soo Kim; Won Young Tak Journal: Clin Mol Hepatol Date: 2013-03-25