Literature DB >> 18336802

Synthesis of UDP-glucose derivatives modified at the 3-OH as potential chain terminators of beta-glucan biosynthesis.

Ramona Danac1, Lucy Ball, Sarah J Gurr, Antony J Fairbanks.   

Abstract

A series of UDP-D-glucose derivatives and precursors that have been modified at C-3 were synthesised from D-glucose as potential chain terminators of beta-glucan biosynthesis. None of the UDP-derivatives or the precursors tested displayed significant anti-fungal activity in a series of germination assays on the dermatophyte Trichophyton rubrum.

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Year:  2008        PMID: 18336802     DOI: 10.1016/j.carres.2008.01.031

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  3 in total

1.  A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis.

Authors:  Jianjun Zhang; Shanteri Singh; Ryan R Hughes; Maoquan Zhou; Manjula Sunkara; Andrew J Morris; Jon S Thorson
Journal:  Chembiochem       Date:  2014-03-21       Impact factor: 3.164

2.  Synthesis of N-acetyl Glucosamine Analogs as Inhibitors for Hyaluronan Biosynthesis.

Authors:  Gilbert Wasonga; Yota Tatara; Ikuko Kakizaki; Xuefei Huang
Journal:  J Carbohydr Chem       Date:  2013-09-02       Impact factor: 1.667

Review 3.  Bioisosteres of Carbohydrate Functional Groups in Glycomimetic Design.

Authors:  Rachel Hevey
Journal:  Biomimetics (Basel)       Date:  2019-07-28
  3 in total

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