Literature DB >> 18336789

Anterior chamber depth and chamber angle and their associations with ocular and general parameters: the Beijing Eye Study.

Liang Xu1, Wei Fang Cao, Ya Xing Wang, Chang Xi Chen, Jost B Jonas.   

Abstract

PURPOSE: To investigate the normative data of anterior chamber depth (ACD) and angle width and their associations in Chinese adults.
DESIGN: Population-based study.
METHODS: The Beijing Eye Study 2006 included 3,251 subjects (73.3%) (aged 45+ years) out of 4,439 subjects who participated in the 2001 survey and who returned for reexamination. The subjects underwent an ophthalmologic examination including measurement of the anterior chamber dimensions by slit-lamp-based optical coherence tomography (OCT).
RESULTS: Out of the 3,251 subjects, OCT measurements were available for 2,985 subjects (91.8%). Mean ACD measured 2.42 +/- 0.34 mm and the mean anterior chamber angle (ACA) was 38.3 +/- 16.3 degrees. In multivariate analysis, a shallow chamber depth was significantly associated with age (P < .001), hyperopic refractive error (P < .001), female gender (P < .001), short body stature (P = .003), nuclear cataract (P = .03), central corneal thickness [CCT] (P < .001), large optic disk (P < .001), and presence of chronic angle-closure glaucoma (P < .001). Correspondingly, a narrow ACA was associated with age (P < .001), female gender (P < .001), hyperopia (P < .001), nuclear cataract (P < .001), short body stature (P = .001), large optic disk (P < .001), and angle-closure glaucoma (P < .001). Chamber depth and angle width were not associated with presence of age-related maculopathy and diabetic retinopathy.
CONCLUSIONS: A shallow anterior chamber and a narrow chamber angle in Chinese adults are associated with age, female gender, hyperopia, nuclear cataract, small optic disk, short body stature, CCT, and chronic angle-closure glaucoma. These data may be helpful to explain anatomic relationships of the anterior segment of the eye, and to elucidate risk factors of angle-closure glaucoma.

Entities:  

Mesh:

Year:  2008        PMID: 18336789     DOI: 10.1016/j.ajo.2008.01.004

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  71 in total

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