Literature DB >> 18336340

Malaria combination therapies: advantages and shortcomings.

A Martinelli1, R Moreira, P V L Ravo.   

Abstract

Drug combination therapies have been devised to delay the development and spread of resistant malaria parasites. However, poor design often leads to ineffective combinations. Here, the properties of various drug combinations are reviewed in relationship to drug resistance and their pharmacokinetic compatibility.

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Year:  2008        PMID： 18336340     DOI： 10.2174/138955708783744092

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  10 in total

Review 1.  Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics.

Authors:  Robert L Summers; Megan N Nash; Rowena E Martin
Journal:  Cell Mol Life Sci       Date:  2012-06       Impact factor: 9.261

2.  Novel endoperoxide-based transmission-blocking antimalarials with liver- and blood-schizontocidal activities.

Authors:  Daniela Miranda; Rita Capela; Inês S Albuquerque; Patrícia Meireles; Isa Paiva; Fátima Nogueira; Richard Amewu; Jiri Gut; Philip J Rosenthal; Rudi Oliveira; Maria M Mota; Rui Moreira; Francesc Marti; Miguel Prudêncio; Paul M O'Neill; Francisca Lopes
Journal:  ACS Med Chem Lett       Date:  2013-12-20       Impact factor: 4.345

3.  Drug combinations as effective anti-leishmanials against drug resistant Leishmania mexicana.

Authors:  Humera Ahmed; Charlotte R Curtis; Sara Tur-Gracia; Toluwanimi O Olatunji; Katharine C Carter; Roderick A M Williams
Journal:  RSC Med Chem       Date:  2020-07-02

4.  Artemisinin-dipeptidyl vinyl sulfone hybrid molecules: design, synthesis and preliminary SAR for antiplasmodial activity and falcipain-2 inhibition.

Authors:  Rita Capela; Rudi Oliveira; Lídia M Gonçalves; Ana Domingos; Jiri Gut; Philip J Rosenthal; Francisca Lopes; Rui Moreira
Journal:  Bioorg Med Chem Lett       Date:  2009-05-03       Impact factor: 2.823

5.  Orally formulated artemisinin in healthy fasting Vietnamese male subjects: a randomized, four-sequence, open-label, pharmacokinetic crossover study.

Authors:  Tran Tinh Hien; Warunee Hanpithakpong; Nguyen Thanh Truong; Nguyen Thi Dung; Pham Van Toi; Jeremy Farrar; Niklas Lindegardh; Joel Tarning; Michael Ashton
Journal:  Clin Ther       Date:  2011-05       Impact factor: 3.393

Review 6.  The Dialogue of the Host-Parasite Relationship: Leishmania spp. and Trypanosoma cruzi Infection.

Authors:  Carlos Gustavo Vieira de Morais; Ana Karina Castro Lima; Rodrigo Terra; Rosiane Freire dos Santos; Silvia Amaral Gonçalves Da-Silva; Patrícia Maria Lourenço Dutra
Journal:  Biomed Res Int       Date:  2015-05-18       Impact factor: 3.411

Review 7.  Ferrocene-Based Compounds with Antimalaria/Anticancer Activity.

Authors:  Sijongesonke Peter; Blessing Atim Aderibigbe
Journal:  Molecules       Date:  2019-10-07       Impact factor: 4.411

8.  Joining forces: Leveraging novel combination therapies to combat infections with eukaryotic pathogens.

Authors:  Rachel E Ham; Lesly A Temesvari
Journal:  PLoS Pathog       Date:  2020-12-31       Impact factor: 6.823

9.  Xylopic acid-amodiaquine and xylopic acid-artesunate combinations are effective in managing malaria in Plasmodium berghei-infected mice.

Authors:  Silas Acheampong Osei; Robert Peter Biney; Ernest Obese; Mary Atta-Panyi Agbenyeku; Isaac Yaw Attah; Elvis Ofori Ameyaw; Johnson Nyarko Boampong
Journal:  Malar J       Date:  2021-02-25       Impact factor: 2.979

Review 10.  Polymeric Nanocarriers for the Delivery of Antimalarials.

Authors:  Zandile Mhlwatika; Blessing Atim Aderibigbe
Journal:  Molecules       Date:  2018-10-02       Impact factor: 4.411
  10 in total

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