Literature DB >> 18335122

Saliva composition and functions: a comprehensive review.

Patricia Del Vigna de Almeida1, Ana Maria Trindade Grégio, Maria Angela Naval Machado, Antonio Adilson Soares de Lima, Luciana Reis Azevedo.   

Abstract

AIM: The aim of this study was to perform a literature review about the composition and functions of saliva as well as describe the factors that influence salivary flow (SF) and its biochemical composition.
BACKGROUND: Saliva represents an increasingly useful auxiliary means of diagnosis. Sialometry and sialochemistry are used to diagnose systemic illnesses, monitoring general health, and as an indicator of risk for diseases creating a close relation between oral and systemic health. REVIEW: This review provides fundamental information about the salivary system in terms of normal values for SF and composition and a comprehensive review of the factors that affect this important system.
CONCLUSION: Since several factors can influence salivary secretion and composition, a strictly standardized collection must be made so the above-mentioned exams are able to reflect the real functioning of the salivary glands and serve as efficient means for monitoring health. CLINICAL SIGNIFICANCE: Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with the current literature on the subject.

Mesh:

Substances:

Year:  2008        PMID: 18335122

Source DB:  PubMed          Journal:  J Contemp Dent Pract        ISSN: 1526-3711


  135 in total

1.  Cannabinoids and metabolites in expectorated oral fluid after 8 days of controlled around-the-clock oral THC administration.

Authors:  Garry Milman; Allan J Barnes; David M Schwope; Eugene W Schwilke; Robert S Goodwin; Deana L Kelly; David A Gorelick; Marilyn A Huestis
Journal:  Anal Bioanal Chem       Date:  2011-06-03       Impact factor: 4.142

2.  The α-test: rapid cell-free CD4 enumeration using whole saliva.

Authors:  Cynthia L Bristow; Mariya A Babayeva; Rozbeh Modarresi; Carole P McArthur; Santosh Kumar; Charles Awasom; Leo Ayuk; Annette Njinda; Paul Achu; Ronald Winston
Journal:  J Vis Exp       Date:  2012-05-16       Impact factor: 1.355

3.  Surface thermodynamic homeostasis of salivary conditioning films through polar-apolar layering.

Authors:  Henny C van der Mei; Don J White; Jelly Atema-Smit; Gésinda I Geertsema-Doornbusch; Henk J Busscher
Journal:  Clin Oral Investig       Date:  2011-02-02       Impact factor: 3.573

4.  An On-Chip Disposable Salivary Glucose Sensor for Diabetes Control.

Authors:  Yunqing Du; Wenjun Zhang; Ming L Wang
Journal:  J Diabetes Sci Technol       Date:  2016-11-01

5.  P2Y2 nucleotide receptor activation enhances the aggregation and self-organization of dispersed salivary epithelial cells.

Authors:  Farid G El-Sayed; Jean M Camden; Lucas T Woods; Mahmoud G Khalafalla; Michael J Petris; Laurie Erb; Gary A Weisman
Journal:  Am J Physiol Cell Physiol       Date:  2014-04-23       Impact factor: 4.249

6.  Influence of orthodontic appliance type on salivary parameters during treatment.

Authors:  Ines Dallel; Intidhar Ben Salem; Abderrahmen Merghni; Wassim Bellalah; Fadoua Neffati; Samir Tobji; Maha Mastouri; Adel Ben Amor
Journal:  Angle Orthod       Date:  2020-07-01       Impact factor: 2.079

7.  Identification of Salivary Proteomic Biomarkers for Oral Cancer Screening.

Authors:  Shigeo Ishikawa; Kenichi Ishizawa; Atsushi Tanaka; Hirohito Kimura; Kenichiro Kitabatake; Ayako Sugano; Kaoru Edamatsu; Shohei Ueda; Mitsuyoshi Iino
Journal:  In Vivo       Date:  2021 Jan-Feb       Impact factor: 2.155

8.  Radiation-induced salivary gland dysfunction results from p53-dependent apoptosis.

Authors:  Jennifer L Avila; Oliver Grundmann; Randy Burd; Kirsten H Limesand
Journal:  Int J Radiat Oncol Biol Phys       Date:  2009-02-01       Impact factor: 7.038

9.  Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles.

Authors:  Masahiro Sugimoto; David T Wong; Akiyoshi Hirayama; Tomoyoshi Soga; Masaru Tomita
Journal:  Metabolomics       Date:  2009-09-10       Impact factor: 4.290

Review 10.  Sensitivity of salivary glands to radiation: from animal models to therapies.

Authors:  O Grundmann; G C Mitchell; K H Limesand
Journal:  J Dent Res       Date:  2009-10       Impact factor: 6.116

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