Literature DB >> 18332172

Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth.

Aldona L Baltch1, William J Ritz, Lawrence H Bopp, Phyllis Michelsen, Raymond P Smith.   

Abstract

We investigated the antistaphylococcal activities of daptomycin, gentamicin, and rifampin against two Staphylococcus aureus strains and their stable small-colony variants, singly and in combination, in human monocyte-derived macrophages and in broth. Intracellularly, the three-drug combination and two-drug combinations with rifampin were most effective. Extracellularly, daptomycin, daptomycin plus gentamicin, gentamicin plus rifampin, and the three-drug combination had similar activities.

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Year:  2008        PMID： 18332172      PMCID： PMC2346650          DOI： 10.1128/AAC.01480-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

1.  Emergence of variant forms of Staphylococcus aureus after exposure to gentamicin and infectivity of the variants in experimental animals.

Authors:  D M Musher; R E Baughn; G B Templeton; J N Minuth
Journal:  J Infect Dis       Date:  1977-09       Impact factor: 5.226

2.  Recovery of small colony variants of Staphylococcus aureus following gentamicin bead placement for osteomyelitis.

Authors:  C von Eiff; D Bettin; R A Proctor; B Rolauffs; N Lindner; W Winkelmann; G Peters
Journal:  Clin Infect Dis       Date:  1997-11       Impact factor: 9.079

3.  Intraphagocytic penetration of antibiotics.

Authors:  P Van der Auwera; T Matsumoto; M Husson
Journal:  J Antimicrob Chemother       Date:  1988-08       Impact factor: 5.790

4.  Decreased susceptibility to antibiotic killing of a stable small colony variant of Staphylococcus aureus in fluid phase and on fibronectin-coated surfaces.

Authors:  C Chuard; P E Vaudaux; R A Proctor; D P Lew
Journal:  J Antimicrob Chemother       Date:  1997-05       Impact factor: 5.790

5.  A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly.

Authors:  C von Eiff; C Heilmann; R A Proctor; C Woltz; G Peters; F Götz
Journal:  J Bacteriol       Date:  1997-08       Impact factor: 3.490

6.  Persistent wound infection after herniotomy associated with small-colony variants of Staphylococcus aureus.

Authors:  M Abele-Horn; B Schupfner; P Emmerling; H Waldner; H Göring
Journal:  Infection       Date:  2000 Jan-Feb       Impact factor: 3.553

7.  Bactericidal action of daptomycin against stationary-phase and nondividing Staphylococcus aureus cells.

Authors:  Carmela T M Mascio; Jeff D Alder; Jared A Silverman
Journal:  Antimicrob Agents Chemother       Date:  2007-10-08       Impact factor: 5.191

8.  Persistence of a Staphylococcus aureus small-colony variant under antibiotic pressure in vivo.

Authors:  Eric Brouillette; Alejandro Martinez; Bobbi J Boyll; Norris E Allen; François Malouin
Journal:  FEMS Immunol Med Microbiol       Date:  2004-05-01

9.  Persistent and relapsing infections associated with small-colony variants of Staphylococcus aureus.

Authors:  R A Proctor; P van Langevelde; M Kristjansson; J N Maslow; R D Arbeit
Journal:  Clin Infect Dis       Date:  1995-01       Impact factor: 9.079

Review 10.  Daptomycin: another novel agent for treating infections due to drug-resistant gram-positive pathogens.

Authors:  Christopher F Carpenter; Henry F Chambers
Journal:  Clin Infect Dis       Date:  2004-03-11       Impact factor: 9.079
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  11 in total

Review 1.  Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections.

Authors:  Barbara C Kahl; Karsten Becker; Bettina Löffler
Journal:  Clin Microbiol Rev       Date:  2016-04       Impact factor: 26.132

Review 2.  Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management.

Authors:  Steven Y C Tong; Joshua S Davis; Emily Eichenberger; Thomas L Holland; Vance G Fowler
Journal:  Clin Microbiol Rev       Date:  2015-07       Impact factor: 26.132

3.  Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype and revertant strains.

Authors:  Hoang Anh Nguyen; Olivier Denis; Anne Vergison; Anne Theunis; Paul M Tulkens; Marc J Struelens; Françoise Van Bambeke
Journal:  Antimicrob Agents Chemother       Date:  2009-02-02       Impact factor: 5.191

4.  Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: study of antibiotic combinations.

Authors:  Hoang Anh Nguyen; Olivier Denis; Anne Vergison; Paul M Tulkens; Marc J Struelens; Françoise Van Bambeke
Journal:  Antimicrob Agents Chemother       Date:  2009-02-02       Impact factor: 5.191

5.  In vitro elution of daptomycin by a synthetic crystallic semihydrate form of calcium sulfate, stimulan.

Authors:  Kyriaki Kanellakopoulou; Periklis Panagopoulos; Efthymia Giannitsioti; Thomas Tsaganos; Dionyssia-Pinelopi Carrer; Nicolas Efstathopoulos; Evangelos J Giamarellos-Bourboulis
Journal:  Antimicrob Agents Chemother       Date:  2009-04-27       Impact factor: 5.191

6.  Staphylococcus aureus persisters tolerant to bactericidal antibiotics.

Authors:  Sabrina Lechner; Kim Lewis; Ralph Bertram
Journal:  J Mol Microbiol Biotechnol       Date:  2012-09-14

7.  Pharmacodynamic evaluation of the activity of antibiotics against hemin- and menadione-dependent small-colony variants of Staphylococcus aureus in models of extracellular (broth) and intracellular (THP-1 monocytes) infections.

Authors:  L G Garcia; S Lemaire; B C Kahl; K Becker; R A Proctor; O Denis; P M Tulkens; F Van Bambeke
Journal:  Antimicrob Agents Chemother       Date:  2012-05-07       Impact factor: 5.191

8.  Dynamic interactions between cephalexin and macrophages on different Staphylococcus aureus inoculum sizes: a tripartite in vitro model.

Authors:  Elodie Anne Lallemand; Claudine Zemirline; Pierre-Louis Toutain; Alain Bousquet-Melou; Aude A Ferran; Séverine Boullier
Journal:  BMC Vet Res       Date:  2021-01-07       Impact factor: 2.741

Review 9.  Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis.

Authors:  Christian Johann Lerche; Franziska Schwartz; Mia Marie Pries-Heje; Emil Loldrup Fosbøl; Kasper Iversen; Peter Østrup Jensen; Niels Høiby; Ole Hyldegaard; Henning Bundgaard; Claus Moser
Journal:  Front Cell Infect Microbiol       Date:  2022-02-03       Impact factor: 5.293

10.  Daptomycin-Nonsusceptible Staphylococcus aureus: The Role of Combination Therapy with Daptomycin and Gentamicin.

Authors:  Jhih-Hang Jiang; Anton Y Peleg
Journal:  Genes (Basel)       Date:  2015-11-30       Impact factor: 4.096
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