| Literature DB >> 18331712 |
Abstract
The regulation of many targets of the Wnt/beta-catenin signaling pathway is thought to occur through a transcriptional switch that is achieved by beta-catenin binding to TCF transcription factors. Recent work indicates that beta-catenin's intrinsic affinity for TCF is not sufficient for the switch to occur.Entities:
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Year: 2008 PMID: 18331712 DOI: 10.1016/j.devcel.2008.02.006
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270