Literature DB >> 18326071

Bladder neck contracture after robot-assisted laparoscopic radical prostatectomy: evaluation of incidence and risk factors and impact on urinary function.

Lambda P Msezane1, W Stuart Reynolds, Ofer N Gofrit, Arieh L Shalhav, Gregory P Zagaja, Kevin C Zorn.   

Abstract

BACKGROUND AND
PURPOSE: Bladder neck contracture (BNC) after radical prostatectomy has been reported to occur in 5% to 32% of men after open retropubic prostatectomy (RRP) and in 0% to 3% after laparoscopic RRP. Optimal anastomotic closure involves creating a watertight, tension-free anastomosis with well-vascularized, mucosal apposition and correct realignment of the urethra. The cause of BNC is poorly understood; however, it is likely related to multiple factors, including excessive luminal narrowing at the site of reconstruction, local tissue ischemia, failed mucosal apposition, and urinary leakage. In this large series of patients who underwent robot-assisted laparoscopic radical prostatectomy (RLRP), we report the incidence of BNC, evaluate the influence of age, body mass index (BMI), estimated blood loss (EBL), surgical time, and prostate weight on its development and assess follow-up urinary function.
METHODS: Between February 2003 and July 2006, 650 consecutive men underwent RLRP at our institution. Patients with aborted or open conversion procedures were excluded from analysis. The mean overall follow-up for the remaining 634 patients was 19.5 months. Patients presenting with symptoms of outlet obstruction were evaluated with cystoscopy to confirm a BNC. Comparisons of age, BMI, EBL, operative time, and prostate weight were performed using the Student t-test and chi-square analysis.
RESULTS: BNC was the diagnosis in seven patients (1.1%) with a mean time of presentation of 4.8 (3-12) months postoperatively. The BNC patients had comparable mean age, BMI, prostate weight, and EBL to the non-BNC cohort. Their operative time, however, was significantly longer (283 v 225 min., P = 0.04).
CONCLUSIONS: The incidence of BNC after radical prostatectomy is 2.2% in a large series of men undergoing RLRP. The diagnosis was made within 1 year. No significant impact on urinary continence or quality-of-life urinary function was observed after BNC management. A running anastomosis, better visualization, improved instrument maneuverability, and decreased blood loss may account for such a low rate.

Entities:  

Mesh:

Year:  2008        PMID: 18326071

Source DB:  PubMed          Journal:  J Endourol        ISSN: 0892-7790            Impact factor:   2.942


  18 in total

Review 1.  [Bladder neck sclerosis following prostate surgery : Which therapy when?]

Authors:  J J Rassweiler; H Weiss; A Heinze; M Elmussareh; M Fiedler; A S Goezen
Journal:  Urologe A       Date:  2017-09       Impact factor: 0.639

2.  Novel method of knotless vesicourethral anastomosis during robot-assisted radical prostatectomy: feasibility study and early outcomes in 30 patients using the interlocked barbed unidirectional V-LOC180 suture.

Authors:  Kevin C Zorn; Hugues Widmer; Jean-Baptiste Lattouf; Dan Liberman; Naeem Bhojani; Quoc-Dien Trinh; Maxine Sun; Pierre I Karakiewicz; Ronald Denis; Assaad El-Hakim
Journal:  Can Urol Assoc J       Date:  2011-06       Impact factor: 1.862

3.  Incidence of bladder neck contracture after robot-assisted laparoscopic and open radical prostatectomy.

Authors:  Benjamin N Breyer; Cole B Davis; Janet E Cowan; Christopher J Kane; Peter R Carroll
Journal:  BJU Int       Date:  2010-12       Impact factor: 5.588

4.  The risk of urinary retention following robot-assisted radical prostatectomy and its impact on early continence outcomes.

Authors:  Mansour Alnazari; Marc Zanaty; Khaled Ajib; Assaad El-Hakim; Kevin C Zorn
Journal:  Can Urol Assoc J       Date:  2017-12-22       Impact factor: 1.862

5.  The impact of bladder neck mucosal eversion during open radical prostatectomy on bladder neck stricture and urinary extravasation.

Authors:  Gita M Schoeppler; Dirk Zaak; Dirk-Andre Clevert; Petra Schuhmann; Oliver Reich; Michael Seitz; Wael Y Khoder; Michael Staehler; Christian G Stief; Alexander Buchner
Journal:  Int Urol Nephrol       Date:  2012-05-15       Impact factor: 2.370

Review 6.  Considering the role of radical prostatectomy in 21st century prostate cancer care.

Authors:  Anthony J Costello
Journal:  Nat Rev Urol       Date:  2020-02-21       Impact factor: 14.432

7.  Vesico-urethral anastomotic stenosis following radical prostatectomy: a multi-institutional outcome analysis with a focus on endoscopic approach, surgical sequence, and the impact of radiation therapy.

Authors:  D Pfalzgraf; T Worst; J Kranz; J Steffens; G Salomon; M Fisch; C P Reiß; M W Vetterlein; C M Rosenbaum
Journal:  World J Urol       Date:  2020-03-31       Impact factor: 4.226

8.  Contemporary radical prostatectomy.

Authors:  Qiang Fu; Judd W Moul; Leon Sun
Journal:  Prostate Cancer       Date:  2011-04-14

9.  Prevalence and risk factors of bladder neck contracture after radical prostatectomy.

Authors:  Hee Ju Cho; Tae Young Jung; Duk Yoon Kim; Seok Soo Byun; Dong Deuk Kwon; Tae Hee Oh; Woo Jin Ko; Tag Keun Yoo
Journal:  Korean J Urol       Date:  2013-05-14

Review 10.  Measuring Quality of Life Following Robot-Assisted Radical Prostatectomy.

Authors:  Graham R Hale; Mohammed Shahait; David I Lee; Daniel J Lee; Ryan W Dobbs
Journal:  Patient Prefer Adherence       Date:  2021-06-23       Impact factor: 2.711

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