Literature DB >> 18318593

Toxicodynamic assumptions in ecotoxicological hazard models.

Roman Ashauer1, Colin D Brown.   

Abstract

Existing toxicokinetic and toxicodynamic models and dynamic formulations of popular ecotoxicological concepts (e.g., the critical body residue concept) are examined. Their underlying assumptions about speed of recovery and thresholds are clarified, and a rigorous mathematical treatment shows that they can all be placed within a unifying framework. Such analysis aids in the selection of appropriate ecotoxicological models.

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Year:  2008        PMID： 18318593     DOI： 10.1897/07-642

Source DB:  PubMed          Journal:  Environ Toxicol Chem        ISSN： 0730-7268            Impact factor:   3.742


  6 in total

1.  Modelling effects of diquat under realistic exposure patterns in genetically differentiated populations of the gastropod Lymnaea stagnalis.

Authors:  Virginie Ducrot; Alexandre R R Péry; Laurent Lagadic
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2010-11-12       Impact factor: 6.237

2.  Toxicodynamic modeling of zebrafish larvae to metals using stochastic death and individual tolerance models: comparisons of model assumptions, parameter sensitivity and predictive performance.

Authors:  Yongfei Gao; Jianfeng Feng; Lin Zhu
Journal:  Ecotoxicology       Date:  2017-02-03       Impact factor: 2.823

3.  A biology-based approach for quantitative structure-activity relationships (QSARs) in ecotoxicity.

Authors:  Tjalling Jager; Sebastiaan A L M Kooijman
Journal:  Ecotoxicology       Date:  2008-10-19       Impact factor: 2.823

4.  Toxicokinetic-toxicodynamic modelling of survival of Gammarus pulex in multiple pulse exposures to propiconazole: model assumptions, calibration data requirements and predictive power.

Authors:  Anna-Maija Nyman; Kristin Schirmer; Roman Ashauer
Journal:  Ecotoxicology       Date:  2012-05-05       Impact factor: 2.823

5.  Modelling survival: exposure pattern, species sensitivity and uncertainty.

Authors:  Roman Ashauer; Carlo Albert; Starrlight Augustine; Nina Cedergreen; Sandrine Charles; Virginie Ducrot; Andreas Focks; Faten Gabsi; André Gergs; Benoit Goussen; Tjalling Jager; Nynke I Kramer; Anna-Maija Nyman; Veronique Poulsen; Stefan Reichenberger; Ralf B Schäfer; Paul J Van den Brink; Karin Veltman; Sören Vogel; Elke I Zimmer; Thomas G Preuss
Journal:  Sci Rep       Date:  2016-07-06       Impact factor: 4.379

6.  Mothers and not genes determine inherited differences in cadmium sensitivities within unexposed populations of the freshwater crustacean Gammarus fossarum.

Authors:  Amandine Vigneron; Olivier Geffard; Hervé Quéau; Arnaud Chaumot
Journal:  Evol Appl       Date:  2015-10-28       Impact factor: 5.183
  6 in total

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