Literature DB >> 1831808

Tolerability and safety of clodronate therapy in bone diseases.

M Mian1, F Beghé, A Caprio, R Aloj, A Bertelli.   

Abstract

A review is made of 126 publications on clinical studies concerning the use of clodronate in the therapy of bone disease involving 1930 patients in order to evaluate the tolerability and the effects following the short-and long-term administration of this drug. The results of the large number of studies indicate that clodronate therapy does not have any clinically significant side-effects and confirm its tolerability and safety.

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Year:  1991        PMID: 1831808

Source DB:  PubMed          Journal:  Int J Clin Pharmacol Res        ISSN: 0251-1649


  6 in total

Review 1.  Adverse effects of bisphosphonates. A comparative review.

Authors:  S Adami; N Zamberlan
Journal:  Drug Saf       Date:  1996-03       Impact factor: 5.606

2.  Erythroderma after clodronate treatment.

Authors:  I Pajus; P Lestang; F Lioté; A Dryll
Journal:  BMJ       Date:  1993-08-21

Review 3.  Clodronate: a review of its use in breast cancer.

Authors:  M Hurst; S Noble
Journal:  Drugs Aging       Date:  1999-08       Impact factor: 3.923

Review 4.  Clodronic acid formulations available in Europe and their use in osteoporosis: a review.

Authors:  Bruno Frediani; Luca Cavalieri; Giovanni Cremonesi
Journal:  Clin Drug Investig       Date:  2009       Impact factor: 2.859

5.  Extended safety profile of oral clodronate after long-term use in primary breast cancer patients.

Authors:  Sari Atula; Trevor Powles; Alexander Paterson; Eugene McCloskey; Jaakko Nevalainen; John Kanis
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

Review 6.  Clodronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease.

Authors:  G L Plosker; K L Goa
Journal:  Drugs       Date:  1994-06       Impact factor: 9.546

  6 in total

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