Literature DB >> 18317489

Outcomes of lower urinary and bowel function in meningomyelocele patients with augmentation enterocystoplasty.

T Mitsui1, H Tanaka, K Moriya, M Matsuda, K Nonomura.   

Abstract

OBJECTIVES: We evaluated the outcomes of augmentation ileocystoplasty in video-urodynamics (V-UDS) and questionnaires related to bowel and urinary function.
METHODS: In 22 meningomyelocele (MMC) patients (11 male and 11 female, a mean age at surgery 14.4 years) who underwent augmentation ileocystoplasties, V-UDS was performed before and at a median of 15 months (6-120 months) after the surgery and the questionnaires were answered at a median of 7.1 years (1.1-14.5 years) after surgery.
RESULTS: Concomitant procedures of urethral sling in four, cecostomy in four and ureteral reimplantation in two were performed at augmentation ileocystoplasty. V-UDS showed a significant improvement after the surgery in bladder capacity, bladder compliance and detrusor overactivity. Vesicoureteral reflux (VUR) disappeared after the surgery in 16 of 19 ureters with VUR. Although questionnaire for urinary condition using International Consultation on Incontinence Questionnaire-Short Form demonstrated that 80% of patients were completely free from urinary incontinence after surgery, more than a half of patients had persistent or deteriorated bowel function such as urgency of bowel movement and fecal incontinence in questionnaires for bowel function. Even with complaints in bowel function, more than 80% of MMC patients had a high level of satisfaction with augmentation enterocystoplasty in overall quality of life (QOL).
CONCLUSIONS: Benefits of augmentation ileocystoplasty were maintained in urodynamic parameters as well as urinary continence. Although augmentation ileocystoplasty generally provides high QOL for MMC patients refractory to conservative therapies, an advance of fecal management can make MMC patients' QOL superior to a current state.

Entities:  

Mesh:

Year:  2008        PMID: 18317489     DOI: 10.1038/sj.sc.3102164

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  3 in total

Review 1.  [Neurogenic bladder function disorders in patients with meningomyelocele: S2k guidelines on diagnostics and therapy].

Authors:  R Stein; C Assion; R Beetz; M Bürst; R Cremer; A Ermert; M Goepel; E Kuwertz-Bröking; B Ludwikowski; T Michael; J Pannek; H Peters; D Rohrmann; I Rübben; A Schröder; R Trollmann; J W Thüroff; W Wagner
Journal:  Urologe A       Date:  2015-02       Impact factor: 0.639

Review 2.  Understanding roles of porcine small intestinal submucosa in urinary bladder regeneration: identification of variable regenerative characteristics of small intestinal submucosa.

Authors:  Hsueh-Kung Lin; Shirley Yezdi Godiwalla; Blake Palmer; Dominic Frimberger; Qing Yang; Sundar V Madihally; Kar-Ming Fung; Bradley P Kropp
Journal:  Tissue Eng Part B Rev       Date:  2013-07-25       Impact factor: 6.389

3.  Impact of posterior urethral diameter/external urethral sphincter diameter as a new tool to predict detrusor pressure in the voiding phase.

Authors:  Masafumi Kon; Takahiko Mitsui; Takeya Kitta; Kimihiko Moriya; Nobuo Shinohara; Masayuki Takeda; Katsuya Nonomura
Journal:  Int Urol Nephrol       Date:  2017-12-14       Impact factor: 2.370

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.