OBJECTIVE: We analyzed the effect of fruit and vegetable intake on lung cancer risk in a population in northwest Spain. METHODS: We analyzed data from a hospital-based case-control study including 295 histologically confirmed cases and 322 controls. Controls were patients attending the hospital for minor surgery. There was a minimum age limit of 35 y and sampling was carried out on a sex-frequency basis. RESULTS: After adjustment for sex, age, tobacco use, and occupation, no protective effect of overall consumption of fruit was present (odds ratio 1.49, 95% confidence interval 0.81-2.73). Green leafy vegetables conferred a protective effect (odds ratio 0.50, 95% confidence interval 0.30-0.83). CONCLUSION: These findings indicate that green leafy vegetables, rather than fruit, might have a genuine protective effect against lung cancer.
OBJECTIVE: We analyzed the effect of fruit and vegetable intake on lung cancer risk in a population in northwest Spain. METHODS: We analyzed data from a hospital-based case-control study including 295 histologically confirmed cases and 322 controls. Controls were patients attending the hospital for minor surgery. There was a minimum age limit of 35 y and sampling was carried out on a sex-frequency basis. RESULTS: After adjustment for sex, age, tobacco use, and occupation, no protective effect of overall consumption of fruit was present (odds ratio 1.49, 95% confidence interval 0.81-2.73). Green leafy vegetables conferred a protective effect (odds ratio 0.50, 95% confidence interval 0.30-0.83). CONCLUSION: These findings indicate that green leafy vegetables, rather than fruit, might have a genuine protective effect against lung cancer.
Authors: Jessie A Satia; Alyson Littman; Christopher G Slatore; Joseph A Galanko; Emily White Journal: Am J Epidemiol Date: 2009-02-10 Impact factor: 4.897
Authors: Christine A Stidley; Maria A Picchi; Shuguang Leng; Randy Willink; Richard E Crowell; Kristina G Flores; Huining Kang; Tim Byers; Frank D Gilliland; Steven A Belinsky Journal: Cancer Res Date: 2010-01-12 Impact factor: 12.701