Literature DB >> 18311619

Survey of furan in heat processed foods by headspace gas chromatography/mass spectrometry and estimated adult exposure.

Kim M Morehouse1, Patricia J Nyman, Timothy P McNeal, Michael J Dinovi, Gracia A Perfetti.   

Abstract

Furan is a suspected human carcinogen that is formed in some processed foods at low ng per g levels. Recent improvements in analytical methodology and scientific instrumentation have made it possible to accurately measure the amount of furan in a wide variety of foods. Results from analysis of more than 300 processed foods are presented. Furan was found at levels ranging from non-detectable (LOD, 0.2-0.9 ng g(-1)) to over 100 ng g(-1). Exposure estimates for several adult food types were calculated, with brewed coffee being the major source of furan in the adult diet (0.15 microg kg(-1) body weight day(-1)). Estimates of mean exposure to furan for different subpopulations were calculated. For consumers 2 years and older, the intake is estimated to be about 0.2 microg kg(-1) body weight day(-1).

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Year:  2008        PMID: 18311619     DOI: 10.1080/02652030701552949

Source DB:  PubMed          Journal:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess        ISSN: 1944-0057


  11 in total

1.  Inhaled Furan Selectively Damages Club Cells in Lungs of A/J Mice.

Authors:  Alexandru-Flaviu Tǎbǎran; M Gerard O'Sullivan; Donna E Seabloom; Karin R Vevang; William E Smith; Timothy S Wiedmann; Lisa A Peterson
Journal:  Toxicol Pathol       Date:  2019-08-19       Impact factor: 1.902

2.  Extra virgin olive oil enhances the hepatic antioxidant defense and inhibits cytogenotoxic effects evoked by 5-hydroxymethylfurfural in mice.

Authors:  Khlood M El Bohi; Mervat H Ghoniem; Haidy H Azab; Haytham Ali; Mayada R Farag
Journal:  Environ Sci Pollut Res Int       Date:  2020-01-24       Impact factor: 4.223

3.  Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study.

Authors:  Linda S Von Tungeln; Nigel J Walker; Greg R Olson; Maria C B Mendoza; Robert P Felton; Brett T Thorn; M Matilde Marques; Igor P Pogribny; Daniel R Doerge; Frederick A Beland
Journal:  Food Chem Toxicol       Date:  2016-11-18       Impact factor: 6.023

4.  Dose- and time-dependent epigenetic changes in the livers of Fisher 344 rats exposed to furan.

Authors:  Aline de Conti; Tetyana Kobets; Claudia Escudero-Lourdes; Beverly Montgomery; Volodymyr Tryndyak; Frederick Alan Beland; Daniel R Doerge; Igor Petrovych Pogribny
Journal:  Toxicol Sci       Date:  2014-03-10       Impact factor: 4.849

5.  Protective role of quercetin against hematotoxic and immunotoxic effects of furan in rats.

Authors:  Rasha T Alam; Ehsan H Abu Zeid; Tamer S Imam
Journal:  Environ Sci Pollut Res Int       Date:  2016-11-26       Impact factor: 4.223

6.  Detailed exposure assessment of dietary furan for infants consuming commercially jarred complementary food based on data from the DONALD study.

Authors:  Dirk W Lachenmeier; Elena Maser; Thomas Kuballa; Helmut Reusch; Mathilde Kersting; Ute Alexy
Journal:  Matern Child Nutr       Date:  2010-12-22       Impact factor: 3.092

7.  Toxicogenomic assessment of liver responses following subchronic exposure to furan in Fischer F344 rats.

Authors:  Hongyan Dong; Santokh Gill; Ivan H Curran; Andrew Williams; Byron Kuo; Michael G Wade; Carole L Yauk
Journal:  Arch Toxicol       Date:  2015-07-21       Impact factor: 5.153

8.  Bioactivity of selected materials for coffee substitute.

Authors:  Renata Zawirska-Wojtasiak; Paulina Piechowska; Elżbieta Wojtowicz; Krzysztof Przygoński; Sylwia Mildner-Szkudlarz
Journal:  PLoS One       Date:  2018-11-15       Impact factor: 3.240

9.  Association of Untargeted Urinary Metabolomics and Lung Cancer Risk Among Never-Smoking Women in China.

Authors:  Wei Jie Seow; Xiao-Ou Shu; Jeremy K Nicholson; Elaine Holmes; Douglas I Walker; Wei Hu; Qiuyin Cai; Yu-Tang Gao; Yong-Bing Xiang; Steven C Moore; Bryan A Bassig; Jason Y Y Wong; Jinming Zhang; Bu-Tian Ji; Claire L Boulangé; Manuja Kaluarachchi; Anisha Wijeyesekera; Wei Zheng; Paul Elliott; Nathaniel Rothman; Qing Lan
Journal:  JAMA Netw Open       Date:  2019-09-04

Review 10.  The Toxicological Aspects of the Heat-Borne Toxicant 5-Hydroxymethylfurfural in Animals: A Review.

Authors:  Mayada R Farag; Mahmoud Alagawany; May Bin-Jumah; Sarah I Othman; Asmaa F Khafaga; Hazem M Shaheen; Dalia Samak; Abdelrazeq M Shehata; Ahmed A Allam; Mohamed E Abd El-Hack
Journal:  Molecules       Date:  2020-04-22       Impact factor: 4.411

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