| Literature DB >> 1830861 |
R H Wenger1, H Hameister, K J Clemetson.
Abstract
Pro-platelet basic protein (pro-PBP) is the precursor of the two platelet alpha-granule proteins, PBP and connective tissue activating peptide-III. Upon platelet activations they are released and further processed in plasma to beta-thromboglobulin and neutrophil-activating peptide-2. The gene encoding pro-PBP is mapped in this study to chromosome 4q12-q13. At least four other members of this family of small inducible cytokines, including NAP-1/Il-8 and platelet factor 4, reside within the same locus, indicating a gene cluster for the beta-thromboglobulin family.Entities:
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Year: 1991 PMID: 1830861 DOI: 10.1007/bf00200921
Source DB: PubMed Journal: Hum Genet ISSN: 0340-6717 Impact factor: 4.132