Literature DB >> 18305354

Unnarmicins A and C, new antibacterial depsipeptides produced by marine bacterium Photobacterium sp. MBIC06485.

Naoya Oku1, Kazutaka Kawabata, Kyoko Adachi, Atsuko Katsuta, Yoshikazu Shizuri.   

Abstract

Two new antibiotic depsipeptides, unnarmicins C (1) and A (2), were isolated from the fermentation broth of a marine bacterium, Photobacterium sp. strain MBIC06485. The structure of 1 was established by spectroscopic studies and chiral analyses of its chemical degradation/conversion products, and that of 2 by comparing its NMR, MS, and CD data with those of 1. Both compounds selectively inhibited the growth of two strains belonging to the genus Pseudovibrio, one of the most prevalent genera in the marine environments within the class Alphaproteobacteria.

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Year:  2008        PMID: 18305354     DOI: 10.1038/ja.2008.103

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  17 in total

Review 1.  Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology.

Authors:  Vedanjali Gogineni; Mark T Hamann
Journal:  Biochim Biophys Acta Gen Subj       Date:  2017-08-24       Impact factor: 3.770

2.  Histone deacetylase inhibitors as a tool to up-regulate new fungal biosynthetic products: isolation of EGM-556, a cyclodepsipeptide, from Microascus sp.

Authors:  Hélène C Vervoort; Marija Drašković; Phillip Crews
Journal:  Org Lett       Date:  2010-12-21       Impact factor: 6.005

3.  Biosynthetic products from a nearshore-derived gram-negative bacterium enable reassessment of the kailuin depsipeptides.

Authors:  Christine M Theodore; Nicholas Lorig-Roach; Patrick C Still; Tyler A Johnson; Marija Drašković; Joshua A Schwochert; Cassandra N Naphen; Mitchell S Crews; Simone A Barker; Frederick A Valeriote; R Scott Lokey; Phillip Crews
Journal:  J Nat Prod       Date:  2015-02-20       Impact factor: 4.050

4.  Solonamides, a Group of Cyclodepsipeptides, Influence Motility in the Native Producer Photobacterium galatheae S2753.

Authors:  Sheng-Da Zhang; Laura Louise Lindqvist; Thomas Isbrandt; Ingrid Lykke Borre; Mario Wibowo; Maike Wennekers Nielsen; Ling Ding; Thomas Ostenfeld Larsen; Lone Gram
Journal:  Appl Environ Microbiol       Date:  2022-08-24       Impact factor: 5.005

5.  Photobacterium arenosum WH24, Isolated from the Gill of Pacific Oyster Crassostrea gigas from the North Sea of Germany: Co-cultivation and Prediction of Virulence.

Authors:  Hani Pira; Chandra Risdian; Mathias Müsken; Peter J Schupp; Joachim Wink
Journal:  Curr Microbiol       Date:  2022-06-15       Impact factor: 2.343

Review 6.  Scrutinizing the scaffolds of marine biosynthetics from different source organisms: Gram-negative cultured bacterial products enter center stage.

Authors:  Patrick C Still; Tyler A Johnson; Christine M Theodore; Steven T Loveridge; Phillip Crews
Journal:  J Nat Prod       Date:  2014-02-26       Impact factor: 4.050

7.  Toxicity of bioactive and probiotic marine bacteria and their secondary metabolites in Artemia sp. and Caenorhabditis elegans as eukaryotic model organisms.

Authors:  Anna Katrin Neu; Maria Månsson; Lone Gram; María J Prol-García
Journal:  Appl Environ Microbiol       Date:  2013-10-18       Impact factor: 4.792

8.  Inhibition of virulence gene expression in Staphylococcus aureus by novel depsipeptides from a marine photobacterium.

Authors:  Maria Mansson; Anita Nielsen; Louise Kjærulff; Charlotte H Gotfredsen; Matthias Wietz; Hanne Ingmer; Lone Gram; Thomas O Larsen
Journal:  Mar Drugs       Date:  2011-12-07       Impact factor: 6.085

Review 9.  Production of bioactive secondary metabolites by marine vibrionaceae.

Authors:  Maria Mansson; Lone Gram; Thomas O Larsen
Journal:  Mar Drugs       Date:  2011-08-25       Impact factor: 6.085

10.  Microbial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementation.

Authors:  Christina Kourtesi; Anthony R Ball; Ying-Ying Huang; Sanjay M Jachak; D Mariano A Vera; Proma Khondkar; Simon Gibbons; Michael R Hamblin; George P Tegos
Journal:  Open Microbiol J       Date:  2013-03-22
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