BACKGROUND: Natural killer (NK)/T-cell lymphoma involving the larynx is a rare entity, and its clinical picture has not been described. METHODS AND RESULTS: A 73-year-old man had a granulomatous tumor involving the larynx. Multiple biopsies over 1 year were needed to reach an accurate diagnosis of NK/T-cell lymphoma. This patient died of the disease despite the use of chemotherapy. CONCLUSION: To the best of our knowledge, this is the second case of primary laryngeal NK/T-cell that illustrates its clinical picture. In the early stage of the disease, this type of tumor can present as granulous tumor-like lesion without a definite destructive lesion. This tumor type should be kept in mind in tumors that are difficult to diagnose, especially in Asian populations. (c) 2008 Wiley Periodicals, Inc. Head Neck, 2008.
BACKGROUND: Natural killer (NK)/T-cell lymphoma involving the larynx is a rare entity, and its clinical picture has not been described. METHODS AND RESULTS: A 73-year-old man had a granulomatous tumor involving the larynx. Multiple biopsies over 1 year were needed to reach an accurate diagnosis of NK/T-cell lymphoma. This patient died of the disease despite the use of chemotherapy. CONCLUSION: To the best of our knowledge, this is the second case of primary laryngeal NK/T-cell that illustrates its clinical picture. In the early stage of the disease, this type of tumor can present as granulous tumor-like lesion without a definite destructive lesion. This tumor type should be kept in mind in tumors that are difficult to diagnose, especially in Asian populations. (c) 2008 Wiley Periodicals, Inc. Head Neck, 2008.