Literature DB >> 18302176

A prospective assessment of auditory startle alterations in rape and physical assault survivors.

Michael G Griffin1.   

Abstract

This study used a prospective design to investigate startle reactivity following trauma exposure. Startle response was evaluated using loud tones during which measures of eyeblink electromyogram (EMG) and heart rate (HR) were collected. Participants were 40 female sexual or physical assault survivors assessed at 1 month and 6 months postassault. There were no significant differences in startle reactivity between posttraumatic stress disorder (PTSD) and non-PTSD groups at the initial assessment. However, at 6 months postassault there was a significantly greater EMG and HR response in the PTSD group as well as a significant increase in startle reactivity from 1 month to 6 months postassault. The findings lend support to a sensitization model of trauma reactivity in which startle response develops over time along with PTSD symptoms.

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Year:  2008        PMID: 18302176     DOI: 10.1002/jts.20300

Source DB:  PubMed          Journal:  J Trauma Stress        ISSN: 0894-9867


  17 in total

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Review 2.  Diagnostic Biomarkers for Posttraumatic Stress Disorder: Promising Horizons from Translational Neuroscience Research.

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Review 3.  Posttraumatic stress disorder, cardiovascular, and metabolic disease: a review of the evidence.

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Journal:  Ann Behav Med       Date:  2010-02

Review 4.  Impaired safety signal learning may be a biomarker of PTSD.

Authors:  Tanja Jovanovic; Andrew Kazama; Jocelyne Bachevalier; Michael Davis
Journal:  Neuropharmacology       Date:  2011-03-04       Impact factor: 5.250

Review 5.  Linking dimensional models of internalizing psychopathology to neurobiological systems: affect-modulated startle as an indicator of fear and distress disorders and affiliated traits.

Authors:  Uma Vaidyanathan; Christopher J Patrick; Bruce N Cuthbert
Journal:  Psychol Bull       Date:  2009-11       Impact factor: 17.737

6.  Epigenetic and immune function profiles associated with posttraumatic stress disorder.

Authors:  Monica Uddin; Allison E Aiello; Derek E Wildman; Karestan C Koenen; Graham Pawelec; Regina de Los Santos; Emily Goldmann; Sandro Galea
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-03       Impact factor: 11.205

7.  How trauma influences cardiovascular responses to stress: contributions of posttraumatic stress and cognitive appraisals.

Authors:  Sharon Y Lee; Crystal L Park; Linda S Pescatello
Journal:  J Behav Med       Date:  2019-06-05

8.  Effects of Threat Context, Trauma History, and Posttraumatic Stress Disorder Status on Physiological Startle Reactivity in Gulf War Veterans.

Authors:  Andrea N Niles; Adam Luxenberg; Thomas C Neylan; Sabra S Inslicht; Anne Richards; Thomas J Metzler; Jennifer Hlavin; Jersey Deng; Aoife O'Donovan
Journal:  J Trauma Stress       Date:  2018-07-30

Review 9.  Psychobiology of PTSD in the acute aftermath of trauma: Integrating research on coping, HPA function and sympathetic nervous system activity.

Authors:  Matthew C Morris; Uma Rao
Journal:  Asian J Psychiatr       Date:  2012-09-06

Review 10.  Biological studies of post-traumatic stress disorder.

Authors:  Roger K Pitman; Ann M Rasmusson; Karestan C Koenen; Lisa M Shin; Scott P Orr; Mark W Gilbertson; Mohammed R Milad; Israel Liberzon
Journal:  Nat Rev Neurosci       Date:  2012-10-10       Impact factor: 34.870

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