BACKGROUND: Posttraumatic stress disorder (PTSD) is a significant risk factor for cardiovascular and metabolic disease. PURPOSE: The purpose of the current review is to evaluate the evidence suggesting that PTSD increases cardiovascular and metabolic risk factors, and to identify possible biomarkers and psychosocial characteristics and behavioral variables that are associated with these outcomes. METHODS: A systematic literature search in the period of 2002-2009 for PTSD, cardiovascular disease, and metabolic disease was conducted. RESULTS: The literature search yielded 78 studies on PTSD and cardiovascular/metabolic disease and biomarkers. CONCLUSIONS: Although the available literature suggests an association of PTSD with cardiovascular disease and biomarkers, further research must consider potential confounds, incorporate longitudinal designs, and conduct careful PTSD assessments in diverse samples to address gaps in the research literature. Research on metabolic disease and biomarkers suggests an association with PTSD, but has not progressed as far as the cardiovascular research.
BACKGROUND:Posttraumatic stress disorder (PTSD) is a significant risk factor for cardiovascular and metabolic disease. PURPOSE: The purpose of the current review is to evaluate the evidence suggesting that PTSD increases cardiovascular and metabolic risk factors, and to identify possible biomarkers and psychosocial characteristics and behavioral variables that are associated with these outcomes. METHODS: A systematic literature search in the period of 2002-2009 for PTSD, cardiovascular disease, and metabolic disease was conducted. RESULTS: The literature search yielded 78 studies on PTSD and cardiovascular/metabolic disease and biomarkers. CONCLUSIONS: Although the available literature suggests an association of PTSD with cardiovascular disease and biomarkers, further research must consider potential confounds, incorporate longitudinal designs, and conduct careful PTSD assessments in diverse samples to address gaps in the research literature. Research on metabolic disease and biomarkers suggests an association with PTSD, but has not progressed as far as the cardiovascular research.
Authors: Robert W Haley; Wanpen Vongpatanasin; Gil I Wolfe; Wilson W Bryan; Roseanne Armitage; Robert F Hoffmann; Frederick Petty; Timothy S Callahan; Elizabeth Charuvastra; William E Shell; W Wesley Marshall; Ronald G Victor Journal: Am J Med Date: 2004-10-01 Impact factor: 4.965
Authors: Ronald C Kessler; Patricia Berglund; Olga Demler; Robert Jin; Kathleen R Merikangas; Ellen E Walters Journal: Arch Gen Psychiatry Date: 2005-06
Authors: Sonya B Norman; Adrienne J Means-Christensen; Michelle G Craske; Cathy D Sherbourne; Peter P Roy-Byrne; Murray B Stein Journal: J Trauma Stress Date: 2006-08
Authors: Viola Vaccarino; Jack Goldberg; Kathryn M Magruder; Christopher W Forsberg; Matthew J Friedman; Brett T Litz; Patrick J Heagerty; Grant D Huang; Theresa C Gleason; Nicholas L Smith Journal: J Psychiatr Res Date: 2014-06-09 Impact factor: 4.791
Authors: Katherine D Hoerster; Lamont Tanksley; Tracy Simpson; Brian E Saelens; Jürgen Unützer; Marissa Black; Preston Greene; Nadiyah Sulayman; Gayle Reiber; Karin Nelson Journal: Am J Health Promot Date: 2020-03-12